Todd J. Sullivan, Ph.D.
Affiliations: | 2005 | Stony Brook University, Stony Brook, NY, United States |
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Parents
Sign in to add mentor| Peter J. Tonge | grad student | 2005 | SUNY Stony Brook | |
| (Developing novel inhibitors of the enoyl reductase from Mycobacterium tuberculosis (InhA): SAR studies of triclosan congeners.) | ||||
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| Sharma H, Landau MJ, Sullivan TJ, et al. (2014) Virtual screening reveals allosteric inhibitors of the Toxoplasma gondii thymidylate synthase-dihydrofolate reductase. Bioorganic & Medicinal Chemistry Letters. 24: 1232-5 |
| Iyidogan P, Sullivan TJ, Chordia MD, et al. (2013) Design, Synthesis, and Antiviral Evaluation of Chimeric Inhibitors of HIV Reverse Transcriptase. Acs Medicinal Chemistry Letters. 4: 1183-8 |
| Bailey CM, Sullivan TJ, Iyidogan P, et al. (2013) Bifunctional inhibition of human immunodeficiency virus type 1 reverse transcriptase: mechanism and proof-of-concept as a novel therapeutic design strategy. Journal of Medicinal Chemistry. 56: 3959-68 |
| Younis Y, Hunter R, Muhanji CI, et al. (2010) [d4U]-spacer-[HI-236] double-drug inhibitors of HIV-1 reverse-transcriptase. Bioorganic & Medicinal Chemistry. 18: 4661-73 |
| England K, am Ende C, Lu H, et al. (2009) Substituted diphenyl ethers as a broad-spectrum platform for the development of chemotherapeutics for the treatment of tularaemia. The Journal of Antimicrobial Chemotherapy. 64: 1052-61 |
| am Ende CW, Knudson SE, Liu N, et al. (2008) Synthesis and in vitro antimycobacterial activity of B-ring modified diaryl ether InhA inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 3029-33 |
| Xu H, Sullivan TJ, Sekiguchi J, et al. (2008) Mechanism and inhibition of saFabI, the enoyl reductase from Staphylococcus aureus. Biochemistry. 47: 4228-36 |
| Boyne ME, Sullivan TJ, amEnde CW, et al. (2007) Targeting fatty acid biosynthesis for the development of novel chemotherapeutics against Mycobacterium tuberculosis: evaluation of A-ring-modified diphenyl ethers as high-affinity InhA inhibitors. Antimicrobial Agents and Chemotherapy. 51: 3562-7 |
| Sullivan TJ, Truglio JJ, Boyne ME, et al. (2006) High affinity InhA inhibitors with activity against drug-resistant strains of Mycobacterium tuberculosis. Acs Chemical Biology. 1: 43-53 |
| Sivaraman S, Sullivan TJ, Johnson F, et al. (2004) Inhibition of the bacterial enoyl reductase FabI by triclosan: a structure-reactivity analysis of FabI inhibition by triclosan analogues. Journal of Medicinal Chemistry. 47: 509-18 |