| Year |
Citation |
Score |
| 2014 |
Sharma H, Landau MJ, Sullivan TJ, Kumar VP, Dahlgren MK, Jorgensen WL, Anderson KS. Virtual screening reveals allosteric inhibitors of the Toxoplasma gondii thymidylate synthase-dihydrofolate reductase. Bioorganic & Medicinal Chemistry Letters. 24: 1232-5. PMID 24440298 DOI: 10.1016/J.Bmcl.2013.12.039 |
0.456 |
|
| 2013 |
Iyidogan P, Sullivan TJ, Chordia MD, Frey KM, Anderson KS. Design, Synthesis, and Antiviral Evaluation of Chimeric Inhibitors of HIV Reverse Transcriptase. Acs Medicinal Chemistry Letters. 4: 1183-8. PMID 24900627 DOI: 10.1021/Ml4002979 |
0.389 |
|
| 2013 |
Bailey CM, Sullivan TJ, Iyidogan P, Tirado-Rives J, Chung R, Ruiz-Caro J, Mohamed E, Jorgensen WL, Jorgensen W, Hunter R, Anderson KS. Bifunctional inhibition of human immunodeficiency virus type 1 reverse transcriptase: mechanism and proof-of-concept as a novel therapeutic design strategy. Journal of Medicinal Chemistry. 56: 3959-68. PMID 23659183 DOI: 10.1021/Jm400160S |
0.38 |
|
| 2010 |
Younis Y, Hunter R, Muhanji CI, Hale I, Singh R, Bailey CM, Sullivan TJ, Anderson KS. [d4U]-spacer-[HI-236] double-drug inhibitors of HIV-1 reverse-transcriptase. Bioorganic & Medicinal Chemistry. 18: 4661-73. PMID 20605472 DOI: 10.1016/J.Bmc.2010.05.025 |
0.365 |
|
| 2009 |
England K, am Ende C, Lu H, Sullivan TJ, Marlenee NL, Bowen RA, Knudson SE, Knudson DL, Tonge PJ, Slayden RA. Substituted diphenyl ethers as a broad-spectrum platform for the development of chemotherapeutics for the treatment of tularaemia. The Journal of Antimicrobial Chemotherapy. 64: 1052-61. PMID 19734171 DOI: 10.1093/Jac/Dkp307 |
0.592 |
|
| 2008 |
am Ende CW, Knudson SE, Liu N, Childs J, Sullivan TJ, Boyne M, Xu H, Gegina Y, Knudson DL, Johnson F, Peloquin CA, Slayden RA, Tonge PJ. Synthesis and in vitro antimycobacterial activity of B-ring modified diaryl ether InhA inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 3029-33. PMID 18457948 DOI: 10.1016/J.Bmcl.2008.04.038 |
0.735 |
|
| 2008 |
Xu H, Sullivan TJ, Sekiguchi J, Kirikae T, Ojima I, Stratton CF, Mao W, Rock FL, Alley MR, Johnson F, Walker SG, Tonge PJ. Mechanism and inhibition of saFabI, the enoyl reductase from Staphylococcus aureus. Biochemistry. 47: 4228-36. PMID 18335995 DOI: 10.1021/Bi800023A |
0.689 |
|
| 2007 |
Boyne ME, Sullivan TJ, amEnde CW, Lu H, Gruppo V, Heaslip D, Amin AG, Chatterjee D, Lenaerts A, Tonge PJ, Slayden RA. Targeting fatty acid biosynthesis for the development of novel chemotherapeutics against Mycobacterium tuberculosis: evaluation of A-ring-modified diphenyl ethers as high-affinity InhA inhibitors. Antimicrobial Agents and Chemotherapy. 51: 3562-7. PMID 17664324 DOI: 10.1128/Aac.00383-07 |
0.682 |
|
| 2006 |
Sullivan TJ, Truglio JJ, Boyne ME, Novichenok P, Zhang X, Stratton CF, Li HJ, Kaur T, Amin A, Johnson F, Slayden RA, Kisker C, Tonge PJ. High affinity InhA inhibitors with activity against drug-resistant strains of Mycobacterium tuberculosis. Acs Chemical Biology. 1: 43-53. PMID 17163639 DOI: 10.1021/Cb0500042 |
0.57 |
|
| 2004 |
Sivaraman S, Sullivan TJ, Johnson F, Novichenok P, Cui G, Simmerling C, Tonge PJ. Inhibition of the bacterial enoyl reductase FabI by triclosan: a structure-reactivity analysis of FabI inhibition by triclosan analogues. Journal of Medicinal Chemistry. 47: 509-18. PMID 14736233 DOI: 10.1021/Jm030182I |
0.553 |
|
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