Sudha Chakrapani
Affiliations: | Case Western Reserve University, Cleveland Heights, OH, United States |
Website:
http://physiology.case.edu/media/faculty_cvs/Chakrapani_CV.pdfGoogle:
"Sudha Chakrapani"Mean distance: 15.52 (cluster 32) | S | N | B | C | P |
Parents
Sign in to add mentor| Anthony Auerbach | grad student | 2000-2004 | SUNY Buffalo | |
| (Mechanisms of nicotinic acetylcholine receptor channel gating: The extracellular domain.) | ||||
| Eduardo Perozo | post-doc | 2003-2008 | Chicago | |
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Publications
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| Kumar A, Kindig K, Rao S, et al. (2022) Structural basis for cannabinoid-induced potentiation of alpha1-glycine receptors in lipid nanodiscs. Nature Communications. 13: 4862 |
| Kumar A, Basak S, Chakrapani S. (2021) Recombinant expression and purification of pentameric ligand-gated ion channels for Cryo-EM structural studies. Methods in Enzymology. 652: 81-103 |
| Gibbs E, Chakrapani S. (2021) Structure, Function and Physiology of 5-Hydroxytryptamine Receptors Subtype 3. Sub-Cellular Biochemistry. 96: 373-408 |
| Basak S, Kumar A, Ramsey S, et al. (2020) High-resolution structures of multiple 5-HTR-setron complexes reveal a novel mechanism of competitive inhibition. Elife. 9 |
| Kumar A, Basak S, Rao S, et al. (2020) Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs. Nature Communications. 11: 3752 |
| Bean BP, Chakrapani S, Hibbs RE. (2020) Decision letter: Cryo-EM analysis of PIP2 regulation in mammalian GIRK channels Elife |
| Basak S, Gicheru Y, Kapoor A, et al. (2019) Molecular mechanism of setron-mediated inhibition of full-length 5-HT receptor. Nature Communications. 10: 3225 |
| Chanda B, Chakrapani S. (2019) Decision letter: Structural and functional characterization of an otopetrin family proton channel Elife |
| Basak S, Gicheru Y, Rao S, et al. (2018) Cryo-EM reveals two distinct serotonin-bound conformations of full-length 5-HT receptor. Nature. 563: 270-274 |
| Gicheru Y, Chakrapani S. (2018) Direct visualization of ion-channel gating in a native environment. Proceedings of the National Academy of Sciences of the United States of America. 115: 10198-10200 |