Thomas Weimbs, Ph.D.

Affiliations: 
1984-1990 Department of Chemistry University of Cologne,  
 1989-1993 Department of Biochemistry, Medical School University of Cologne, Köln, Nordrhein-Westfalen, Germany 
 1993-1999 Department of Anatomy University of California, San Francisco, San Francisco, CA 
 1999-2005 Department of Cell Biology The Cleveland Clinic, Cleveland, OH, United States 
 2005- Department of Molecular, Cellular, and Developmental Biology University of California, Santa Barbara, Santa Barbara, CA, United States 
Area:
polycystic kidney disease, membrane trafficking, SNARE membrane fusion proteins
Website:
https://labs.mcdb.ucsb.edu/weimbs/thomas/
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Parents

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Wilhelm Stoffel grad student 1990-1993 University of Cologne
Keith E. Mostov post-doc 1994-1999 UCSF (Cell Biology Tree)

Children

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Hannah Pellegrini grad student 2017- UC Santa Barbara
Elizabeth Sharpe grad student 2018- UC Santa Barbara
Nickolas Holznecht grad student 2020- UC Santa Barbara
Nikunj Sharma grad student 2002-2007 Cleveland State University
Shivakumar Vasanth grad student 2003-2007 Kent State
Jeffrey J. Talbot grad student 2013 UC Santa Barbara
Nicholas Doerr grad student 2007-2014 UC Santa Barbara
Erin Olsan grad student 2007-2014 UC Santa Barbara
Adrian Giovannone grad student 2008-2014 UC Santa Barbara
Kevin Kipp grad student 2011-2016 UC Santa Barbara
Jacob Torres grad student 2011-2017 UC Santa Barbara
Pallavi Bhattaram post-doc 2004-2006 UC Santa Barbara
Elena Reales post-doc 2006-2010 UC Santa Barbara
Jonathan Shillingford post-doc 2003-2012 UC Santa Barbara
Christine Winterstein post-doc 2007-2012 UC Santa Barbara
Guangyi Liu post-doc 2015-2016 UC Santa Barbara
Sebastian Strubl post-doc 2019-2022 UC Santa Barbara
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Publications

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Torres JA, Holznecht N, Asplund DA, et al. (2023) A Combination of ß-Hydroxybutyrate and Citrate Ameliorates Disease Progression in a Rat Model of Polycystic Kidney Disease. American Journal of Physiology. Renal Physiology
Cukoski S, Lindemann CH, Arjune S, et al. (2023) Feasibility and impact of ketogenic dietary interventions in polycystic kidney disease: KETO-ADPKD-a randomized controlled trial. Cell Reports. Medicine. 101283
Pellegrini H, Sharpe EH, Liu G, et al. (2023) Cleavage fragments of the C-terminal tail of polycystin-1 are regulated by oxidative stress and induce mitochondrial dysfunction. The Journal of Biological Chemistry. 105158
Akbari M, West JD, Doerr N, et al. (2022) Restoration of atypical protein kinase C ζ function in autosomal dominant polycystic kidney disease ameliorates disease progression. Proceedings of the National Academy of Sciences of the United States of America. 119: e2121267119
Tonum K, Srimai N, Chabang N, et al. (2022) Pharmacological Effects of Panduratin A on Renal Cyst Development in In Vitro and In Vivo Models of Polycystic Kidney Disease. International Journal of Molecular Sciences. 23
Strubl S, Oehm S, Torres JA, et al. (2021) Ketogenic dietary interventions in autosomal dominant polycystic kidney disease-a retrospective case series study: first insights into feasibility, safety and effects. Clinical Kidney Journal. 15: 1079-1092
Giovannone AJ, Reales E, Bhattaram P, et al. (2020) The H domain of syntaxin 3 is a ubiquitin binding domain. Scientific Reports. 10: 21350
Dafinger C, Mandel AM, Braun A, et al. (2020) The carboxy-terminus of the human ARPKD protein fibrocystin can control STAT3 signalling by regulating SRC-activation. Journal of Cellular and Molecular Medicine
Strubl S, Torres JA, Spindt AK, et al. (2020) STAT signaling in polycystic kidney disease. Cellular Signalling. 72: 109639
Torres JA, Kruger SL, Broderick C, et al. (2019) Ketosis Ameliorates Renal Cyst Growth in Polycystic Kidney Disease. Cell Metabolism
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