Kelly R. Bales, Ph.D.

Affiliations: 
2007 Medical Neurobiology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Neuroscience
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"Kelly Bales"
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Parents

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Yansheng Du grad student 2007 Indiana University
 (Interaction of the beta-amyloid protein in Alzheimer's disease and the choline transporter.)
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Publications

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Bales KR, Paul SM. (2019) Targeting apolipoprotein E for treating Alzheimer's disease. Neuroscience Letters. 134366
Deming Y, Xia J, Cai Y, et al. (2016) Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits Scientific Reports. 6
Deming Y, Xia J, Cai Y, et al. (2015) A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin. Neurobiology of Aging
Bales KR, O'Neill SM, Pozdnyakov N, et al. (2015) Passive immunotherapy targeting amyloid-β reduces cerebral amyloid angiopathy and improves vascular reactivity. Brain : a Journal of Neurology
Pettersson M, Johnson DS, Humphrey JM, et al. (2015) Design of Pyridopyrazine-1,6-dione γ-Secretase Modulators that Align Potency, MDR Efflux Ratio, and Metabolic Stability. Acs Medicinal Chemistry Letters. 6: 596-601
Pettersson M, Johnson DS, Humphrey JM, et al. (2015) Discovery of indole-derived pyridopyrazine-1,6-dione γ-secretase modulators that target presenilin. Bioorganic & Medicinal Chemistry Letters. 25: 908-13
Kauwe JS, Bailey MH, Ridge PG, et al. (2014) Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation. Plos Genetics. 10: e1004758
Harari O, Cruchaga C, Kauwe JS, et al. (2014) Phosphorylated tau-Aβ42 ratio as a continuous trait for biomarker discovery for early-stage Alzheimer's disease in multiplex immunoassay panels of cerebrospinal fluid. Biological Psychiatry. 75: 723-31
Pettersson M, Johnson DS, Subramanyam C, et al. (2014) Design, synthesis, and pharmacological evaluation of a novel series of pyridopyrazine-1,6-dione γ-secretase modulators. Journal of Medicinal Chemistry. 57: 1046-62
Pozdnyakov N, Murrey HE, Crump CJ, et al. (2013) γ-Secretase modulator (GSM) photoaffinity probes reveal distinct allosteric binding sites on presenilin. The Journal of Biological Chemistry. 288: 9710-20
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