Kelly R. Bales, Ph.D.
Affiliations: | 2007 | Medical Neurobiology | Indiana University, Bloomington, Bloomington, IN, United States |
Area:
NeuroscienceGoogle:
"Kelly Bales"Mean distance: 42746.4
Parents
Sign in to add mentor| Yansheng Du | grad student | 2007 | Indiana University | |
| (Interaction of the beta-amyloid protein in Alzheimer's disease and the choline transporter.) | ||||
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Publications
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| Xu J, Sun J, Perrin RJ, et al. (2019) Translocator protein in late stage Alzheimer's disease and Dementia with Lewy bodies brains. Annals of Clinical and Translational Neurology. 6: 1423-1434 |
| O'Neill BT, Beck EM, Butler CR, et al. (2018) Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-site amyloid precursor protein cleaving enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation. Journal of Medicinal Chemistry |
| Dresselhaus E, Duerr JM, Vincent F, et al. (2018) Class I HDAC inhibition is a novel pathway for regulating astrocytic apoE secretion. Plos One. 13: e0194661 |
| Zhang L, Chen L, Dutra JK, et al. (2018) Identification of a novel positron emission tomography (PET) ligand for imaging β-site amyloid precursor protein cleaving enzyme 1 (BACE-1) in brain. Journal of Medicinal Chemistry |
| Pettersson M, Johnson DS, Rankic DA, et al. (2017) Discovery of cyclopropyl chromane-derived pyridopyrazine-1,6-dione γ-secretase modulators with robust central efficacy. Medchemcomm. 8: 730-743 |
| Van Eldik LJ, Carrillo MC, Cole PE, et al. (2016) The roles of inflammation and immune mechanisms in Alzheimer's disease. Alzheimer's & Dementia (New York, N. Y.). 2: 99-109 |
| Deming Y, Xia J, Cai Y, et al. (2015) A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin. Neurobiology of Aging |
| Bales KR, O'Neill SM, Pozdnyakov N, et al. (2015) Passive immunotherapy targeting amyloid-β reduces cerebral amyloid angiopathy and improves vascular reactivity. Brain : a Journal of Neurology |
| Pettersson M, Johnson DS, Humphrey JM, et al. (2015) Design of Pyridopyrazine-1,6-dione γ-Secretase Modulators that Align Potency, MDR Efflux Ratio, and Metabolic Stability. Acs Medicinal Chemistry Letters. 6: 596-601 |
| Pettersson M, Johnson DS, Humphrey JM, et al. (2015) Discovery of indole-derived pyridopyrazine-1,6-dione γ-secretase modulators that target presenilin. Bioorganic & Medicinal Chemistry Letters. 25: 908-13 |