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Warren D. Hirst

Affiliations: 
Imperial College, London, London, England, United Kingdom 
Area:
astrocytes
Google:
"Warren Hirst"
Mean distance: 17.78 (cluster 11)
 
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Parents

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Graham P. Wilkin grad student Imperial College

Children

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Katrina L. Paumier post-doc 2010-2013 Pfizer, Inc.

Collaborators

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Publications

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Ugbode CI, Smith I, Whalley BJ, et al. (2017) SHH signalling mediates astrocyte crosstalk with neurons to confer neuroprotection. Journal of Neurochemistry
Volpicelli-Daley LA, Abdelmotilib H, Liu Z, et al. (2016) G2019S-LRRK2 Expression Augments α-Synuclein Sequestration into Inclusions in Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7415-27
Delenclos M, Trendafilova T, Jones DR, et al. (2015) A Rapid, Semi-Quantitative Assay to Screen for Modulators of Alpha-Synuclein Oligomerization Ex vivo. Frontiers in Neuroscience. 9: 511
Norkett R, Modi S, Birsa N, et al. (2015) DISC1-dependent Regulation of Mitochondrial Dynamics Controls the Morphogenesis of Complex Neuronal Dendrites. The Journal of Biological Chemistry
Henry AG, Aghamohammadzadeh S, Samaroo H, et al. (2015) Pathogenic LRRK2 mutations, through increased kinase activity, produce enlarged lysosomes with reduced degradative capacity and increase ATP13A2 expression. Human Molecular Genetics. 24: 6013-28
Daher JP, Abdelmotilib HA, Hu X, et al. (2015) LRRK2 Pharmacological Inhibition Abates α-Synuclein Induced Neurodegeneration. The Journal of Biological Chemistry
Henderson JL, Kormos BL, Hayward MM, et al. (2015) Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor. Journal of Medicinal Chemistry. 58: 419-32
Ugbode CI, Hirst WD, Rattray M. (2014) Neuronal influences are necessary to produce mitochondrial co-localization with glutamate transporters in astrocytes. Journal of Neurochemistry. 130: 668-77
Birsa N, Norkett R, Wauer T, et al. (2014) Lysine 27 ubiquitination of the mitochondrial transport protein Miro is dependent on serine 65 of the Parkin ubiquitin ligase. The Journal of Biological Chemistry. 289: 14569-82
Shen W, Henry AG, Paumier KL, et al. (2014) Inhibition of glucosylceramide synthase stimulates autophagy flux in neurons. Journal of Neurochemistry. 129: 884-94
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