Leigh A. Needleman

Affiliations: 
Harvard University, HHMI, Cambridge, MA, United States 
Area:
synapse development and plasticity
Google:
"Leigh Needleman"
Mean distance: 13.85 (cluster 6)
 
SNBCP

Parents

Sign in to add mentor
George W. Huntley research assistant 1998-2000 Mount Sinai School of Medicine
John Marshall grad student 2000-2006 Brown
 (Regulation of kainate receptors at the synapse.)
A. Kimberly McAllister post-doc 2007- UC Davis
Catherine Dulac research scientist 2011- Harvard
BETA: Related publications

Publications

You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.

Needleman LA, McAllister AK. (2012) The major histocompatibility complex and autism spectrum disorder. Developmental Neurobiology. 72: 1288-301
Glynn MW, Elmer BM, Garay PA, et al. (2011) MHCI negatively regulates synapse density during the establishment of cortical connections. Nature Neuroscience. 14: 442-51
Needleman LA, Liu XB, El-Sabeawy F, et al. (2010) MHC class I molecules are present both pre- and postsynaptically in the visual cortex during postnatal development and in adulthood. Proceedings of the National Academy of Sciences of the United States of America. 107: 16999-7004
Needleman LA, McAllister AK. (2008) Seeing the light: insulin receptors and the CNS. Neuron. 58: 653-5
Salinas GD, Blair LA, Needleman LA, et al. (2006) Actinfilin is a Cul3 substrate adaptor, linking GluR6 kainate receptor subunits to the ubiquitin-proteasome pathway. The Journal of Biological Chemistry. 281: 40164-73
Gao L, Blair LA, Salinas GD, et al. (2006) Insulin-like growth factor-1 modulation of CaV1.3 calcium channels depends on Ca2+ release from IP3-sensitive stores and calcium/calmodulin kinase II phosphorylation of the alpha1 subunit EF hand. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6259-68
Ren Z, Riley NJ, Needleman LA, et al. (2003) Cell surface expression of GluR5 kainate receptors is regulated by an endoplasmic reticulum retention signal. The Journal of Biological Chemistry. 278: 52700-9
Poskanzer K, Needleman LA, Bozdagi O, et al. (2003) N-cadherin regulates ingrowth and laminar targeting of thalamocortical axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2294-305
Bekirov IH, Needleman LA, Zhang W, et al. (2002) Identification and localization of multiple classic cadherins in developing rat limbic system. Neuroscience. 115: 213-27
Gil OD, Needleman L, Huntley GW. (2002) Developmental patterns of cadherin expression and localization in relation to compartmentalized thalamocortical terminations in rat barrel cortex. The Journal of Comparative Neurology. 453: 372-88
See more...