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Kristen Mary Shannon O'Connell

Affiliations: 
2016- Research The Jackson Laboratory, Bar Harbor, ME, United States 
Area:
Ion channels
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"Kristen O'Connell"
Mean distance: 15.85 (cluster 32)
 		SNBCP
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Parents

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Robert T. Dirksen grad student 1997-2003 Rochester
 (Regulation of excitation-contraction coupling and L-type Ca(2+) channel activation in skeletal muscle by calmodulin and prolonged depolarization.)
Michael M. Tamkun post-doc 2002-2008 Colorado State

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Publications

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Baver SB, Hope K, Guyot S, et al. (2014) Leptin modulates the intrinsic excitability of AgRP/NPY neurons in the arcuate nucleus of the hypothalamus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5486-96
O'Connell KM, Guyot S, Baver SB. (2013) Obesity Influences the Regulation of the Intrinsic Excitability of AgRP/NPY Neurons by Leptin Biophysical Journal. 104: 162a
Baver SB, O'Connell KM. (2012) The C-terminus of neuronal Kv2.1 channels is required for channel localization and targeting but not for NMDA-receptor-mediated regulation of channel function. Neuroscience. 217: 56-66
O'Connell KM, Loftus R, Tamkun MM. (2010) Localization-dependent activity of the Kv2.1 delayed-rectifier K+ channel. Proceedings of the National Academy of Sciences of the United States of America. 107: 12351-6
O'Connell KM, Whitesell JD, Tamkun MM. (2008) Localization and mobility of the delayed-rectifer K+ channel Kv2.1 in adult cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. 294: H229-37
Tamkun MM, O'connell KM, Rolig AS. (2007) A cytoskeletal-based perimeter fence selectively corrals a sub-population of cell surface Kv2.1 channels. Journal of Cell Science. 120: 2413-23
O'Connell KM, Rolig AS, Whitesell JD, et al. (2006) Kv2.1 potassium channels are retained within dynamic cell surface microdomains that are defined by a perimeter fence. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9609-18
O'Connell KM, Tamkun MM. (2005) Targeting of voltage-gated potassium channel isoforms to distinct cell surface microdomains. Journal of Cell Science. 118: 2155-66
Weiss RG, O'Connell KM, Flucher BE, et al. (2004) Functional analysis of the R1086H malignant hyperthermia mutation in the DHPR reveals an unexpected influence of the III-IV loop on skeletal muscle EC coupling. American Journal of Physiology. Cell Physiology. 287: C1094-102
O'Connell KM, Martens JR, Tamkun MM. (2004) Localization of ion channels to lipid Raft domains within the cardiovascular system. Trends in Cardiovascular Medicine. 14: 37-42
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