Harry T. Orr
Affiliations: | Neuroscience | University of Minnesota, Twin Cities, Minneapolis, MN |
Area:
Neuroscience Biology, Cell BiologyWebsite:
https://med.umn.edu/bio/lab-med-and-pathology-faculty/harry-orrGoogle:
"Harry Orr"Bio:
https://books.google.com/books?id=-iooAQAAIAAJ
Mean distance: 25.48
Parents
Sign in to add mentorAdolph Irvin Cohen | grad student | 1976 | Washington University | |
(Retinal neurochemistry: studies on amino acid transmitter candidates and cyclic nucleotides) | ||||
Oliver H. Lowry | grad student | 1976 | Washington University |
Children
Sign in to add traineeBeverly H. Koller | grad student | 1985 | UMN (Cell Biology Tree) |
Christopher R. Brodie | grad student | 2002 | UMN |
Brigit E. Riley | grad student | 2004 | UMN |
Nathan D. Jorgensen | grad student | 2007 | UMN |
Kristin M. Gehrking | grad student | 2009 | UMN |
Shaojuan Lai | grad student | 2011 | UMN |
Judit Perez-Ortiz | grad student | 2012-2016 | UMN |
Sarita Lagalwar | post-doc | 2008-2012 | UMN |
Margaret E. Flanagan | research scientist | 2017-2019 | UMN |
BETA: Related publications
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Publications
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Coffin SL, Durham MA, Nitschke L, et al. (2022) Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1. Neuron |
Lee WS, Al-Ramahi I, Jeong HH, et al. (2022) Cross-species genetic screens identify transglutaminase 5 as a regulator of polyglutamine-expanded ataxin-1. The Journal of Clinical Investigation. 132 |
Nitschke L, Coffin SL, Xhako E, et al. (2021) Modulation of ATXN1 S776 phosphorylation reveals the importance of allele-specific targeting in SCA1. Jci Insight. 6 |
O'Callaghan B, Hofstra B, Handler HP, et al. (2020) Antisense Oligonucleotide Therapeutic Approach for Suppression of Ataxin-1 Expression: A Safety Assessment. Molecular Therapy. Nucleic Acids. 21: 1006-1016 |
Mouro Pinto R, Arning L, Giordano JV, et al. (2020) Patterns of CAG repeat instability in the central nervous system and periphery in Huntington's disease and in spinocerebellar ataxia type 1. Human Molecular Genetics |
Zhang S, Williamson NA, Duvick L, et al. (2020) The ataxin-1 interactome reveals direct connection with multiple disrupted nuclear transport pathways. Nature Communications. 11: 3343 |
Chuang CS, Chang JC, Soong BW, et al. (2019) Treadmill training increases the motor activity and neuron survival of the cerebellum in a mouse model of spinocerebellar ataxia type 1. The Kaohsiung Journal of Medical Sciences |
Friedrich J, Kordasiewicz HB, O'Callaghan B, et al. (2018) Antisense oligonucleotide-mediated ataxin-1 reduction prolongs survival in SCA1 mice and reveals disease-associated transcriptome profiles. Jci Insight. 3 |
De Maio A, Yalamanchili HK, Adamski CJ, et al. (2018) RBM17 Interacts with U2SURP and CHERP to Regulate Expression and Splicing of RNA-Processing Proteins. Cell Reports. 25: 726-736.e7 |
Bondar VV, Adamski CJ, Onur TS, et al. (2018) PAK1 regulates ATXN1 levels providing an opportunity to modify its toxicity in Spinocerebellar ataxia type 1. Human Molecular Genetics |