Harry T. Orr

Affiliations: 
Neuroscience University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Neuroscience Biology, Cell Biology
Website:
https://med.umn.edu/bio/lab-med-and-pathology-faculty/harry-orr
Google:
"Harry Orr"
Bio:

https://books.google.com/books?id=-iooAQAAIAAJ

Mean distance: 25.48
 

Parents

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Adolph Irvin Cohen grad student 1976 Washington University
 (Retinal neurochemistry: studies on amino acid transmitter candidates and cyclic nucleotides)
Oliver H. Lowry grad student 1976 Washington University

Children

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Beverly H. Koller grad student 1985 UMN (Cell Biology Tree)
Christopher R. Brodie grad student 2002 UMN
Brigit E. Riley grad student 2004 UMN
Nathan D. Jorgensen grad student 2007 UMN
Kristin M. Gehrking grad student 2009 UMN
Shaojuan Lai grad student 2011 UMN
Judit Perez-Ortiz grad student 2012-2016 UMN
Sarita Lagalwar post-doc 2008-2012 UMN
Margaret E. Flanagan research scientist 2017-2019 UMN
BETA: Related publications

Publications

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Cendelin J, Cvetanovic M, Gandelman M, et al. (2021) Consensus Paper: Strengths and Weaknesses of Animal Models of Spinocerebellar Ataxias and Their Clinical Implications. Cerebellum (London, England)
Lee WS, Lavery L, Rousseaux MWC, et al. (2021) Dual targeting of brain region-specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1. The Embo Journal. e106106
Nitschke L, Coffin SL, Xhako E, et al. (2021) Modulation of ATXN1 S776 phosphorylation reveals the importance of allele-specific targeting in SCA1. Jci Insight. 6
Chopra R, Bushart DD, Cooper JP, et al. (2020) Altered Capicua expression drives regional Purkinje neuron vulnerability through ion channel gene dysregulation in spinocerebellar ataxia type 1. Human Molecular Genetics
O'Callaghan B, Hofstra B, Handler HP, et al. (2020) Antisense Oligonucleotide Therapeutic Approach for Suppression of Ataxin-1 Expression: A Safety Assessment. Molecular Therapy. Nucleic Acids. 21: 1006-1016
Mouro Pinto R, Arning L, Giordano JV, et al. (2020) Patterns of CAG repeat instability in the central nervous system and periphery in Huntington's disease and in spinocerebellar ataxia type 1. Human Molecular Genetics
Zhang S, Williamson NA, Duvick L, et al. (2020) The ataxin-1 interactome reveals direct connection with multiple disrupted nuclear transport pathways. Nature Communications. 11: 3343
Chao OY, de Velasco EMF, Pathak SS, et al. (2020) Targeting inhibitory cerebellar circuitry to alleviate behavioral deficits in a mouse model for studying idiopathic autism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Chuang CS, Chang JC, Soong BW, et al. (2019) Treadmill training increases the motor activity and neuron survival of the cerebellum in a mouse model of spinocerebellar ataxia type 1. The Kaohsiung Journal of Medical Sciences
Friedrich J, Kordasiewicz HB, O'Callaghan B, et al. (2018) Antisense oligonucleotide-mediated ataxin-1 reduction prolongs survival in SCA1 mice and reveals disease-associated transcriptome profiles. Jci Insight. 3
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