Patricia Brown
Affiliations: | Neuroscience | McGill University, Montreal, QC, Canada |
Area:
Excitatory and Inhibitory Ligand-Gated Ion ChannelsGoogle:
"Patricia Brown"Mean distance: 16.65 (cluster 11) | S | N | B | C | P |
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Publications
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Perozzo AM, Brown PMGE, Bowie D. (2023) Alternative splicing of the flip/flop cassette and TARP auxiliary subunits engage in a privileged relationship that fine-tunes AMPA receptor gating. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience |
Khanra N, Brown PM, Perozzo AM, et al. (2021) Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor. Elife. 10 |
Brown PMGE, McGuire H, Bowie D. (2017) Stargazin and cornichon-3 relieve polyamine block of AMPA receptors by enhancing blocker permeation. The Journal of General Physiology |
Paramo T, Brown PMGE, Musgaard M, et al. (2017) Functional Validation of Heteromeric Kainate Receptor Models. Biophysical Journal |
Krogsgaard-Larsen N, Delgar CG, Koch K, et al. (2016) Design and Synthesis of a Series of l-trans-4-Substituted Prolines as Selective Antagonists for the Ionotropic Glutamate Receptors Including Functional and X-ray Crystallographic Studies of New Subtype Selective Kainic Acid Receptor Subtype 1 (GluK1) Antagonist (2S,4R)-4-(2-Carboxyphenoxy)pyrrolidine-2-carboxylic Acid. Journal of Medicinal Chemistry |
Paramo T, Brown PM, Aurousseau MR, et al. (2016) Functional and Structural Characterization of the GluK2/GluK5 Heterotetramer Gating Mechanism Biophysical Journal. 110: 289a |
Brown PM, Aurousseau MR, Musgaard M, et al. (2015) Kainate receptor pore-forming and auxiliary subunits regulate channel block by a novel mechanism. The Journal of Physiology |
Accardi MV, Brown PM, Miraucourt LS, et al. (2015) α6-Containing GABAA Receptors Are the Principal Mediators of Inhibitory Synapse Strengthening by Insulin in Cerebellar Granule Cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 9676-88 |
Demmer CS, Møller C, Brown PM, et al. (2015) Binding Mode of an α-Amino Acid-Linked Quinoxaline-2,3-dione Analogue at Glutamate Receptor Subtype GluK1. Acs Chemical Neuroscience. 6: 845-54 |
Penna A, Wang DS, Yu J, et al. (2014) Hydrogen peroxide increases GABAA receptor-mediated tonic current in hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 10624-34 |