Alan L. Pehrson

Affiliations: 
Neuroscience University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Cogntion, schizophrenia, behavioral pharmacology, microdialysis
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"Alan Pehrson"
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Parents

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Joseph H. Porter grad student 2001-2007 VCU
 (The effects of early postnatal PCP administration on performance in locomotor activity, reference memory, and working memory tasks in C57BL/6 mice.)
Bita Moghaddam post-doc 2007- University of Pittsburgh
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Publications

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Hillhouse TM, Merritt CR, Smith DA, et al. (2018) Vortioxetine Differentially Modulates MK-801-Induced Changes in Visual Signal Detection Task Performance and Locomotor Activity. Frontiers in Pharmacology. 9: 1024
Prus AJ, Wise LE, Pehrson AL, et al. (2016) Discriminative stimulus properties of 1.25 mg/kg clozapine in rats: mediation by serotonin 5-HT2and dopamine D4 receptors. Brain Research
Pehrson AL, Hillhouse TM, Haddjeri N, et al. (2016) Task- and treatment length-dependent effects of vortioxetine on scopolamine-induced cognitive dysfunction and hippocampal extracellular acetylcholine in rats. The Journal of Pharmacology and Experimental Therapeutics
Smagin GN, Song D, Budac DP, et al. (2016) Histamine may contribute to vortioxetine's procognitive effects; possibly through an orexigenic mechanism. Progress in Neuro-Psychopharmacology & Biological Psychiatry
Dale E, Pehrson AL, Jeyarajah T, et al. (2015) Effects of serotonin in the hippocampus: how SSRIs and multimodal antidepressants might regulate pyramidal cell function. Cns Spectrums. 1-19
Li Y, Pehrson AL, Waller JA, et al. (2015) A critical evaluation of the activity-regulated cytoskeleton-associated protein (Arc/Arg3.1)'s putative role in regulating dendritic plasticity, cognitive processes, and mood in animal models of depression. Frontiers in Neuroscience. 9: 279
Leiser SC, Iglesias-Bregna D, Westrich L, et al. (2015) Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 2, pharmacological interactions in rodents suggest a role of serotonin-3 receptor antagonism. Journal of Psychopharmacology (Oxford, England). 29: 1092-105
Prus AJ, Mooney-Leber SM, Berquist MD, et al. (2015) The antidepressant drugs fluoxetine and duloxetine produce anxiolytic-like effects in a schedule-induced polydipsia paradigm in rats: enhancement of fluoxetine's effects by the α2 adrenoceptor antagonist yohimbine. Behavioural Pharmacology. 26: 489-94
Li Y, Abdourahman A, Tamm JA, et al. (2015) Reversal of age-associated cognitive deficits is accompanied by increased plasticity-related gene expression after chronic antidepressant administration in middle-aged mice. Pharmacology, Biochemistry, and Behavior. 135: 70-82
Leiser SC, Li Y, Pehrson AL, et al. (2015) Serotonergic Regulation of Prefrontal Cortical Circuitries Involved in Cognitive Processing: A Review of Individual 5-HT Receptor Mechanisms and Concerted Effects of 5-HT Receptors Exemplified by the Multimodal Antidepressant Vortioxetine. Acs Chemical Neuroscience. 6: 970-86
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