Reza Esfandiary, Ph.D.

Affiliations: 
2009 Pharmaceutical Chemistry University of Kansas, Lawrence, KS, United States 
Area:
Pharmaceutical Chemistry
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"Reza Esfandiary"

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Charles Russell Middaugh grad student 2009 University of Kansas (Chemistry Tree)
 (Understanding structural stability of pharmaceutically relevant macromolecular complexes: A biophysical and biochemical approach.)
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Publications

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Shahfar H, Du Q, Parupudi A, et al. (2022) Electrostatically Driven Protein-Protein Interactions: Quantitative Prediction of Second Osmotic Virial Coefficients to Aid Antibody Design. The Journal of Physical Chemistry Letters. 1366-1372
Chaturvedi SK, Parupudi A, Juul-Madsen K, et al. (2020) Measuring aggregates, self-association, and weak interactions in concentrated therapeutic antibody solutions. Mabs. 12: 1810488
Larson NR, Wei Y, Prajapati I, et al. (2019) Comparison of polysorbate 80 hydrolysis and oxidation on the aggregation of a monoclonal antibody. Journal of Pharmaceutical Sciences
Prajapati I, Peters BH, Larson NR, et al. (2019) Cis/trans isomerization of unsaturated fatty acids in polysorbate 80 during light exposure of a monoclonal antibody-containing formulation. Journal of Pharmaceutical Sciences
Austerberry J, Thistlethwaite A, Fisher K, et al. (2019) Arginine to lysine mutations increase the aggregation stability of a single chain variable fragment through unfolded state interactions. Biochemistry
Hu Y, Arora J, Joshi SB, et al. (2019) Characterization of Excipient Effects on Reversible Self-association, Backbone Flexibility, and Solution Properties of an IgG1 Monoclonal Antibody at High Concentrations: Part 1. Journal of Pharmaceutical Sciences
Hu Y, Toth RT, Joshi SB, et al. (2019) Characterization of Excipient Effects on Reversible Self-association, Backbone Flexibility, and Solution Properties of an IgG1 Monoclonal Antibody at High Concentrations: Part 2. Journal of Pharmaceutical Sciences
Shan L, Mody N, Sormanni P, et al. (2018) Developability assessment of engineered monoclonal antibody variants with a complex self-association behavior using complementary analytical and in silico tools. Molecular Pharmaceutics
Toth RT, Pace SE, Mills BJ, et al. (2017) Evaluation of Hydrogen Exchange Mass Spectrometry as a Stability-Indicating Method for Formulation Excipient Screening for an IgG4 Monoclonal Antibody. Journal of Pharmaceutical Sciences
Toth RT, Mills BJ, Joshi SB, et al. (2017) Correction to Empirical Correction for Differences in Chemical Exchange Rates in Hydrogen Exchange-Mass Spectrometry Measurements. Analytical Chemistry. 89: 13673
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