Christine McDonald, Ph.D.
Affiliations: | 1995-2001 | Pathology | Stony Brook University, Stony Brook, NY, United States |
2001-2006 | Pathology | University of Michigan, Ann Arbor, Ann Arbor, MI | |
2006-2018 | Pathobiology | The Cleveland Clinic, Cleveland, OH, United States | |
2018- | Inflammation & Immunity | The Cleveland Clinic, Cleveland, OH, United States |
Area:
Molecular Biology, Innate Immunity, Host Response to Infection, Inflammatory Bowel Disease,PathologyGoogle:
"Christine McDonald"Parents
Sign in to add mentorNancy Reich | grad student | 1995-2001 | SUNY Stony Brook | |
(Functional characterization of the interleukin -4 activated transcription factor, STAT6.) | ||||
Jack E. Dixon | post-doc | 2001-2003 | (Chemistry Tree) | |
(Activation of host kinases by Yersinia effector protein, YopM) | ||||
Gabriel Nunez | post-doc | 2003-2006 | University of Michigan | |
(Identification of regulatory proteins of the pattern recognition receptor NOD2) |
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Publications
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Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, et al. (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382 |
Farabaugh KT, Krokowski D, Guan BJ, et al. (2020) PACT-mediated PKR activation acts as a hyperosmotic stress intensity sensor weakening osmoadaptation and enhancing inflammation. Elife. 9 |
Billi AC, Ludwig JE, Fritz Y, et al. (2020) KLK6 expression in skin induces PAR1-mediated psoriasiform dermatitis and inflammatory joint disease. The Journal of Clinical Investigation |
Scheraga RG, Abraham S, Grove LM, et al. (2020) TRPV4 Protects the Lung from Bacterial Pneumonia via MAPK Molecular Pathway Switching. Journal of Immunology (Baltimore, Md. : 1950) |
Nickerson KP, Chanin R, McDonald C. (2015) Deregulation of intestinal anti-microbial defense by the dietary additive, maltodextrin Gut Microbes. 6: 78-83 |
Warner N, Burberry A, Pliakas M, et al. (2014) A genome-wide small interfering RNA (siRNA) screen reveals nuclear factor-κB (NF-κB)-independent regulators of NOD2-induced interleukin-8 (IL-8) secretion. The Journal of Biological Chemistry. 289: 28213-24 |
Homer CR, Nickerson KP, Corridoni D, et al. (2014) Sa1765 Defective Autophagy Contributes to Impaired Bacterial Clearance of SAMP1/YITFC Mice Gastroenterology. 146 |
Tang H, Amara U, Tang D, et al. (2013) Synergistic interaction between C5a and NOD2 signaling in the regulation of chemokine expression in RAW 264.7 macrophages. Advances in Bioscience and Biotechnology (Print). 4: 30-37 |
Corridoni D, Kodani T, Rodriguez-Palacios A, et al. (2013) Dysregulated NOD2 predisposes SAMP1/YitFc mice to chronic intestinal inflammation. Proceedings of the National Academy of Sciences of the United States of America. 110: 16999-7004 |
Warner N, Burberry A, Franchi L, et al. (2013) A genome-wide siRNA screen reveals positive and negative regulators of the NOD2 and NF-κB signaling pathways. Science Signaling. 6: rs3 |