P. Michael Conn
Affiliations: | Oregon National Primate Research Center, Beaverton, OR, United States |
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| Tao YX, Conn PM. (2018) Pharmacoperones as Novel Therapeutics for Diverse Protein Conformational Diseases. Physiological Reviews. 98: 697-725 |
| Janovick JA, Spicer TP, Bannister TD, et al. (2017) Pharmacoperone rescue of vasopressin 2 receptor mutants reveals unexpected constitutive activity and coupling bias. Plos One. 12: e0181830 |
| Janovick JA, Spicer TP, Smith E, et al. (2016) Receptor antagonism/agonism can be uncoupled from pharmacoperone activity. Molecular and Cellular Endocrinology |
| Ulloa-Aguirre A, Conn PM. (2016) Pharmacoperones as a New Therapeutic Approach: In vitro Identification and In vivo Validation of Bioactive Molecules. Current Drug Targets |
| Conn PM, Spicer TP, Scampavia L, et al. (2015) Assay strategies for identification of therapeutic leads that target protein trafficking. Trends in Pharmacological Sciences. 36: 498-505 |
| Conn PM, Smith E, Spicer T, et al. (2014) A phenotypic high throughput screening assay for the identification of pharmacoperones for the gonadotropin releasing hormone receptor. Assay and Drug Development Technologies. 12: 238-46 |
| Houck SA, Ren HY, Madden VJ, et al. (2014) Quality control autophagy degrades soluble ERAD-resistant conformers of the misfolded membrane protein GnRHR. Molecular Cell. 54: 166-79 |
| Tao YX, Conn PM. (2014) Chaperoning G protein-coupled receptors: from cell biology to therapeutics. Endocrine Reviews. 35: 602-47 |
| Ulloa-Aguirre A, Zariñán T, Dias JA, et al. (2014) Mutations in G protein-coupled receptors that impact receptor trafficking and reproductive function. Molecular and Cellular Endocrinology. 382: 411-23 |
| Ulloa-Aguirre A, Conn PM. (2014) Intracellular Trafficking of G Protein-Coupled Receptors to the Plasma Membrane in Health and Disease Cellular Endocrinology in Health and Disease. 341-364 |