Megan E. Mefford, Ph.D.
Affiliations: | 2012 | Biology: Medical Sciences, Division of | Harvard University, Cambridge, MA, United States |
Area:
Virology Biology, Bioinformatics BiologyGoogle:
"Megan Mefford"Parents
Sign in to add mentor| Dana Gabuzda | grad student | 2012 | Harvard | |
| (Molecular and bioinformatic analysis of neurotropic HIV envelope glycoproteins.) | ||||
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Publications
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| Mefford ME, Kunstman K, Wolinsky SM, et al. (2015) Bioinformatic analysis of neurotropic HIV envelope sequences identifies polymorphisms in the gp120 bridging sheet that increase macrophage-tropism through enhanced interactions with CCR5. Virology. 481: 210-22 |
| Yen PJ, Mefford ME, Hoxie JA, et al. (2014) Identification and characterization of a macrophage-tropic SIV envelope glycoprotein variant in blood from early infection in SIVmac251-infected macaques. Virology. 458: 53-68 |
| Mates JM, Kumar SB, Bazan J, et al. (2014) Genotypic and phenotypic heterogeneity in the U3R region of HIV type 1 subtype C. Aids Research and Human Retroviruses. 30: 102-12 |
| Ancuta P, Kamat A, Kunstman KJ, et al. (2013) Upregulation of CD69 and CCR5 expression on CD16+ and CD16− monocyte subsets. Plos One |
| Holman AG, Mefford ME, O'Connor N, et al. (2010) HIVBrainSeqDB: a database of annotated HIV envelope sequences from brain and other anatomical sites. Aids Research and Therapy. 7: 43 |
| Haim H, Si Z, Madani N, et al. (2009) Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state. Plos Pathogens. 5: e1000360 |
| Mefford ME, Gorry PR, Kunstman K, et al. (2008) Bioinformatic prediction programs underestimate the frequency of CXCR4 usage by R5X4 HIV type 1 in brain and other tissues. Aids Research and Human Retroviruses. 24: 1215-20 |
| Ancuta P, Kamat A, Kunstman KJ, et al. (2008) Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. Plos One. 3: e2516 |
| Dunfee R, Thomas E, Mefford M, et al. (2008) HIV Infection of brain macrophages and microglia Bmc Proceedings. 2: S11 |
| Gorry PR, Dunfee RL, Mefford ME, et al. (2007) Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote. Virology. 362: 163-78 |