Megan E. Mefford, Ph.D. - Publications

Affiliations: 
2012 Biology: Medical Sciences, Division of Harvard University, Cambridge, MA, United States 
Area:
Virology Biology, Bioinformatics Biology

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Mefford ME, Kunstman K, Wolinsky SM, Gabuzda D. Bioinformatic analysis of neurotropic HIV envelope sequences identifies polymorphisms in the gp120 bridging sheet that increase macrophage-tropism through enhanced interactions with CCR5. Virology. 481: 210-22. PMID 25797607 DOI: 10.1016/J.Virol.2015.01.032  0.767
2014 Yen PJ, Mefford ME, Hoxie JA, Williams KC, Desrosiers RC, Gabuzda D. Identification and characterization of a macrophage-tropic SIV envelope glycoprotein variant in blood from early infection in SIVmac251-infected macaques. Virology. 458: 53-68. PMID 24928039 DOI: 10.1016/J.Virol.2014.03.024  0.69
2014 Mates JM, Kumar SB, Bazan J, Mefford M, Voronkin I, Handelman S, Mwapasa V, Ackerman W, Janies D, Kwiek JJ. Genotypic and phenotypic heterogeneity in the U3R region of HIV type 1 subtype C. Aids Research and Human Retroviruses. 30: 102-12. PMID 23826737 DOI: 10.1089/Aid.2013.0026  0.517
2013 Ancuta P, Kamat A, Kunstman KJ, Kim E, Autissier P, Wurcel A, Zaman T, Stone D, Mefford M, Morgello S, Singer EJ, Wolinsky SM, Gabuzda D. Upregulation of CD69 and CCR5 expression on CD16+ and CD16− monocyte subsets. Plos One. DOI: 10.1371/Journal.Pone.0002516.G006  0.486
2010 Holman AG, Mefford ME, O'Connor N, Gabuzda D. HIVBrainSeqDB: a database of annotated HIV envelope sequences from brain and other anatomical sites. Aids Research and Therapy. 7: 43. PMID 21156070 DOI: 10.1186/1742-6405-7-43  0.733
2009 Haim H, Si Z, Madani N, Wang L, Courter JR, Princiotto A, Kassa A, DeGrace M, McGee-Estrada K, Mefford M, Gabuzda D, Smith AB, Sodroski J. Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state. Plos Pathogens. 5: e1000360. PMID 19343205 DOI: 10.1371/Journal.Ppat.1000360  0.656
2008 Mefford ME, Gorry PR, Kunstman K, Wolinsky SM, Gabuzda D. Bioinformatic prediction programs underestimate the frequency of CXCR4 usage by R5X4 HIV type 1 in brain and other tissues. Aids Research and Human Retroviruses. 24: 1215-20. PMID 18788913 DOI: 10.1089/Aid.2008.0009  0.699
2008 Ancuta P, Kamat A, Kunstman KJ, Kim EY, Autissier P, Wurcel A, Zaman T, Stone D, Mefford M, Morgello S, Singer EJ, Wolinsky SM, Gabuzda D. Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. Plos One. 3: e2516. PMID 18575590 DOI: 10.1371/Journal.Pone.0002516  0.637
2008 Dunfee R, Thomas E, Mefford M, Ancuta P, Kamat A, Kunstman K, Wolinsky S, Gabuzda D. HIV Infection of brain macrophages and microglia Bmc Proceedings. 2: S11. DOI: 10.1186/1753-6561-2-s1-s11  0.768
2007 Gorry PR, Dunfee RL, Mefford ME, Kunstman K, Morgan T, Moore JP, Mascola JR, Agopian K, Holm GH, Mehle A, Taylor J, Farzan M, Wang H, Ellery P, Willey SJ, et al. Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote. Virology. 362: 163-78. PMID 17239419 DOI: 10.1016/J.Virol.2006.11.025  0.476
2004 Lederman MM, Veazey RS, Offord RE, Mosier DE, Dufour J, Mefford M, Piatak M, Lifson JD, Salkowitz JR, Rodriguez B, Blauvelt A, Hartley O. Prevention of Vaginal SHIV Transmission in Rhesus Macaques Through Inhibition of CCR5 Science. 306: 485-487. PMID 15486300 DOI: 10.1126/Science.1099288  0.562
2004 Smith SM, Mefford M, Sodora D, Klase Z, Singh M, Alexander N, Hess D, Marx PA. Topical estrogen protects against SIV vaginal transmission without evidence of systemic effect. Aids (London, England). 18: 1637-43. PMID 15280774 DOI: 10.1097/01.Aids.0000131393.76221.Cc  0.471
2004 Ramsburg E, Rose NF, Marx PA, Mefford M, Nixon DF, Moretto WJ, Montefiori D, Earl P, Moss B, Rose JK. Highly effective control of an AIDS virus challenge in macaques by using vesicular stomatitis virus and modified vaccinia virus Ankara vaccine vectors in a single-boost protocol. Journal of Virology. 78: 3930-40. PMID 15047809 DOI: 10.1128/Jvi.78.8.3930-3940.2004  0.362
2003 Veazey RS, Klasse PJ, Ketas TJ, Reeves JD, Piatak M, Kunstman K, Kuhmann SE, Marx PA, Lifson JD, Dufour J, Mefford M, Pandrea I, Wolinsky SM, Doms RW, DeMartino JA, et al. Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection. The Journal of Experimental Medicine. 198: 1551-62. PMID 14623909 DOI: 10.1084/Jem.20031266  0.548
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