James C. Lo, Ph.D.

Affiliations: 
2004 University of Chicago, Chicago, IL 
Area:
Cell Biology, Molecular Biology, Immunology
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"James Lo"

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Yang-Xin Fu grad student 2004 Chicago
 (Lymphotoxin signaling via the NF-kappaB pathway coordinates central and peripheral immune responses.)
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Publications

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Gómez-Banoy N, Lo JC. (2019) Adipokines as key players in β cell function and failure. Clinical Science (London, England : 1979). 133: 2317-2327
Gómez-Banoy N, Guseh JS, Li G, et al. (2019) Adipsin preserves beta cells in diabetic mice and associates with protection from type 2 diabetes in humans. Nature Medicine
Khandekar MJ, Banks AS, Laznik-Bogoslavski D, et al. (2018) Noncanonical agonist PPARγ ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapy. Proceedings of the National Academy of Sciences of the United States of America
Svensson KJ, Long JZ, Jedrychowski MP, et al. (2016) A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function. Cell Metabolism
Kong X, Banks A, Liu T, et al. (2014) IRF4 is a key thermogenic transcriptional partner of PGC-1α. Cell. 158: 69-83
Lo JC, Ljubicic S, Leibiger B, et al. (2014) Adipsin is an adipokine that improves β cell function in diabetes. Cell. 158: 41-53
Rao RR, Long JZ, White JP, et al. (2014) Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis. Cell. 157: 1279-91
Cohen P, Levy JD, Zhang Y, et al. (2014) Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch. Cell. 156: 304-16
Gupta RK, Mepani RJ, Kleiner S, et al. (2012) Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells. Cell Metabolism. 15: 230-9
Boström P, Wu J, Jedrychowski MP, et al. (2012) A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. 481: 463-8
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