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Juan C. Piña-Crespo

Affiliations: 
1989-2006 School of Veterinary Sciences Universidad Centroccidental, Barquisimeto, Venezuela 
 1993-1998 Department of Pharmacology University College London (UCL), England, UK 
 1998-2008 Molecular Neurobiology Laboratory Salk Institute for Biological Studies, La Jolla, CA, United States 
 2008-2020 Neuroscience and Aging Research Center Sanford-Burnham-Prebys Medical Discovery Institute 
 2020-2022 Department of Molecular Medicine Scripps Research Institute, La Jolla, La Jolla, CA, United States 
 2022- Center for Genetic Disorders & Aging Research SBP Medical Discovery Institute 
Area:
Receptors & Ion Channels
Website:
www.sbpdiscovery.org
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"Juan Piña-Crespo"
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Parents

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Nelson L. Dalo research assistant 1989-1990 Univ. Centroccidental, Venezuela
Alasdair J. Gibb grad student 1993-1998 UCL
Steve F. Heinemann post-doc 1998-2008 Salk Institute
Joachim Spiess research scientist
Stuart A. Lipton research scientist 2008-2015 Sanford Burnham Institute
Huaxi Xu research scientist 2015-2020 SBP Medical Discovery Institute

Children

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Joel Grayson Yancey research assistant 2018-2019 SBP Medical Discovery Institute
Sara Sanz-Blasco post-doc ININFA, UBA-CONICET
YU SUN post-doc 2017-2019 SBP Medical Discovery Institute

Collaborators

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Joachim Spiess collaborator SBP Medical Discovery Institute
BETA: Related publications

Publications

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Oh CK, Piña-Crespo J, Talantova M, et al. (2023) Reply to: Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection. Nature Chemical Biology. 19: 1306-1308
Oh CK, Nakamura T, Beutler N, et al. (2022) Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection. Nature Chemical Biology
Zhu B, Liu Y, Hwang S, et al. (2022) Trem2 deletion enhances tau dispersion and pathology through microglia exosomes. Molecular Neurodegeneration. 17: 58
Oh CK, Nakamura T, Beutler N, et al. (2022) Targeted protein S-nitrosylation of ACE2 as potential treatment to prevent spread of SARS-CoV-2 infection. Biorxiv : the Preprint Server For Biology
Trudler D, Sanz-Blasco S, Eisele YS, et al. (2021) α-Synuclein Oligomers Induce Glutamate Release from Astrocytes and Excessive Extrasynaptic NMDAR Activity in Neurons, Thus Contributing to Synapse Loss. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Venkatasubramanian PN, Pina-Crespo JC, Mathews K, et al. (2020) Initial Biphasic Fractional Anisotropy Response to Blast-Induced Mild Traumatic Brain Injury in a Mouse Model. Military Medicine. 185: 243-247
Jia L, Piña-Crespo J, Li Y. (2019) Restoring Wnt/β-catenin signaling is a promising therapeutic strategy for Alzheimer's disease. Molecular Brain. 12: 104
Jiang LL, Zhu B, Zhao Y, et al. (2019) Membralin deficiency dysregulates astrocytic glutamate homeostasis leading to ALS-like impairment. The Journal of Clinical Investigation. 130
Okamoto SI, Prikhodko O, Pina-Crespo J, et al. (2019) NitroSynapsin for the treatment of neurological manifestations of tuberous sclerosis complex in a rodent model. Neurobiology of Disease
Zhao Y, Wu X, Li X, et al. (2018) TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function. Neuron. 97: 1023-1031.e7
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