Seppo Kaakkola

Affiliations: 
University of Helsinki, Helsingfors, Finland 
Area:
neurology
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"Seppo Kaakkola"
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Publications

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Janhunen S, Mielikäinen P, Paldánius P, et al. (2005) The effect of nicotine in combination with various dopaminergic drugs on nigrostriatal dopamine in rats. Naunyn-Schmiedeberg's Archives of Pharmacology. 371: 480-91
Heikkinen H, Varhe A, Laine T, et al. (2002) Entacapone improves the availability of L-dopa in plasma by decreasing its peripheral metabolism independent of L-dopa/carbidopa dose. British Journal of Clinical Pharmacology. 54: 363-71
Lyytinen J, Kaakkola S, Ahtila S, et al. (1997) Simultaneous MAO-B and COMT inhibition in L-Dopa-treated patients with Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 12: 497-505
Ahtila S, Kaakkola S, Gordin A, et al. (1995) Effect of entacapone, a COMT inhibitor, on the pharmacokinetics and metabolism of levodopa after administration of controlled-release levodopa-carbidopa in volunteers. Clinical Neuropharmacology. 18: 46-57
Kaakkola S, Teräväinen H, Ahtila S, et al. (1994) Effect of entacapone, a COMT inhibitor, on clinical disability and levodopa metabolism in parkinsonian patients. Neurology. 44: 77-80
Törnwall M, Kaakkola S, Tuomainen P, et al. (1994) Comparison of two new inhibitors of catechol O-methylation on striatal dopamine metabolism: a microdialysis study in rats. British Journal of Pharmacology. 112: 13-8
Kaakkola S, Wurtman RJ. (1993) Effects of catechol-O-methyltransferase inhibitors and L-3,4-dihydroxyphenylalanine with or without carbidopa on extracellular dopamine in rat striatum. Journal of Neurochemistry. 60: 137-44
Kaakkola S, Wurtman RJ. (1993) Effects of two diketopiperazines, cyclo (His-Pro) and cyclo (Asp-Phe), on striatal dopamine: a microdialysis study. Brain Research Bulletin. 32: 667-72
Kaakkola S, Tuomainen P, Wurtman RJ, et al. (1992) Effects of systemic carbidopa on dopamine synthesis in rat hypothalamus and striatum. Journal of Neural Transmission. Parkinson's Disease and Dementia Section. 4: 143-54
Gardier AM, Kaakkola S, Erfurth A, et al. (1992) Effects of methiothepin on changes in brain serotonin release induced by repeated administration of high doses of anorectic serotoninergic drugs. Brain Research. 588: 67-74
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