Orest Hurko, M.D.

Clinical Biologics Consulting Group, Inc. 
Mendelian disorders
"Orest Hurko"

Undergraduate thesis at Harvard College with Helga Doty, graduate studies with Richard Wurtman at MIT, and MD from Harvard. Staff Associate with Marshall Nirenberg at NIH then Chief Resident then faculty in Neurology at Johns Hopkins, where he was the neurologist in the Moore Genetics Clinical and Author-Editor of Mendelian Inheritance in Man with Victor McKusick. Founded Investigational Medicine in Neuroscience at SmithKline Beecham, Investigational Medicine (Neurology) at GSK, and then the interdisciplinary Discovery Medicine at Wyeth. Director of trnaslational Medicine Research Collaboration in Scotland

Mean distance: 13.91 (cluster 11)
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Hurko O. (2014) The Skin and Neurologic Disease Aminoff's Neurology and General Medicine: Fifth Edition. 401-430
Berger JR, Choi D, Kaminski HJ, et al. (2013) Importance and hurdles to drug discovery for neurological disease. Annals of Neurology. 74: 441-6
Hurko O. (2013) Drug development for rare mitochondrial disorders. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 10: 286-306
Hurko O. (2012) Target-based drug discovery, genetic diseases, and biologics. Neurochemistry International. 61: 892-8
Hurko O, Black SE, Doody R, et al. (2012) The ADNI Publication Policy: commensurate recognition of critical contributors who are not authors. Neuroimage. 59: 4196-200
Hurko O, Jones GK. (2011) Valuation of biomarkers. Nature Reviews. Drug Discovery. 10: 253-4
Hurko O, Boudonck K, Gonzales C, et al. (2010) Ablation of the locus coeruleus increases oxidative stress in tg-2576 transgenic but not wild-type mice. International Journal of Alzheimer's Disease. 2010: 864625
Hurko O. (2010) Future drug discovery and development. Molecular Genetics and Metabolism. 100: S92-6
Hurko O. (2009) The uses of biomarkers in drug development. Annals of the New York Academy of Sciences. 1180: 1-10
Chavez JC, Hurko O, Barone FC, et al. (2009) Pharmacologic interventions for stroke: looking beyond the thrombolysis time window into the penumbra with biomarkers, not a stopwatch. Stroke; a Journal of Cerebral Circulation. 40: e558-63
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