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Karen Duff, PhD

Pathology and Cell Biology Columbia University, New York, NY 
Understanding the molecular basis of neurodegenerative and neuropsychiatric diseases.
"Karen Duff"
Mean distance: 18.91 (cluster 28)
Cross-listing: Alzheimer's Tree - Cell Biology Tree

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Taddei RN, Perbet R, Mate de Gerando A, et al. (2023) Tau Oligomer-Containing Synapse Elimination by Microglia and Astrocytes in Alzheimer Disease. Jama Neurology. 80: 1209-1221
Karakatsani ME, Ji R, Murillo MF, et al. (2023) Focused ultrasound mitigates pathology and improves spatial memory in Alzheimer's mice and patients. Theranostics. 13: 4102-4120
Langworth-Green C, Patel S, Jaunmuktane Z, et al. (2023) Chronic effects of inflammation on tauopathies. The Lancet. Neurology. 22: 430-442
Chen S, Chang Y, Li L, et al. (2022) Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer's disease. Acta Neuropathologica Communications. 10: 188
Chen S, Acosta D, Li L, et al. (2022) Wolframin is a novel regulator of tau pathology and neurodegeneration. Acta Neuropathologica
Miranda AM, Ashok A, Chan RB, et al. (2022) Effects of APOE4 allelic dosage on lipidomic signatures in the entorhinal cortex of aged mice. Translational Psychiatry. 12: 129
Blaudin de Thé FX, Lassus B, Schaler AW, et al. (2021) P62 accumulates through neuroanatomical circuits in response to tauopathy propagation. Acta Neuropathologica Communications. 9: 177
Meisl G, Hidari E, Allinson K, et al. (2021) In vivo rate-determining steps of tau seed accumulation in Alzheimer's disease. Science Advances. 7: eabh1448
Schaler AW, Runyan AM, Clelland CL, et al. (2021) PAC1 receptor-mediated clearance of tau in postsynaptic compartments attenuates tau pathology in mouse brain. Science Translational Medicine. 13
Fung CW, Guo J, Fu H, et al. (2020) Atrophy associated with tau pathology precedes overt cell death in a mouse model of progressive tauopathy. Science Advances. 6
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