Christian G. Specht, Ph.D.

Affiliations: 
2021- Inserm U1195, Université Paris-Saclay Diseases and Hormones of the Nervous System (DHNS) 
Area:
synuclein, inhibitory synapses, GABA receptors, single molecule localisation microscopy (SMLM), quantitative neurobiology
Website:
https://www.researchgate.net/profile/Christian-Specht
Google:
"Christian Specht"
Mean distance: 14.82 (cluster 59)
 
SNBCP

Parents

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Kenneth B.M. Reid research assistant 1994-1995 Oxford
Peter Ruppersberg grad student 1997-1998 Universität Tübingen
Ralf Schoepfer grad student 1998-2005 LMP/University College London
 (PhD in 2002)
Craig C. Garner post-doc 2005-2007 Stanford
Antoine Triller post-doc 2007-2011 ENS Paris
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Publications

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Khayenko V, Schulte C, Reis SL, et al. (2022) A Versatile Synthetic Affinity Probe Reveals Inhibitory Synapse Ultrastructure and Brain Connectivity. Angewandte Chemie (International Ed. in English)
Maynard SA, Rostaing P, Schaefer N, et al. (2021) Identification of a stereotypic molecular arrangement of endogenous glycine receptors at spinal cord synapses. Elife. 10
Specht CG. (2021) A Quantitative Perspective of Alpha-Synuclein Dynamics - Why Numbers Matter. Frontiers in Synaptic Neuroscience. 13: 753462
Yang X, Le Corronc H, Legendre P, et al. (2021) Differential regulation of glycinergic and GABAergic nanocolumns at mixed inhibitory synapses. Embo Reports. e52154
Wagner S, Lee C, Rojas L, et al. (2021) The α3 subunit of GABA receptors promotes formation of inhibitory synapses in the absence of collybistin. The Journal of Biological Chemistry. 100709
Chapdelaine T, Hakim V, Triller A, et al. (2021) Reciprocal stabilisation of glycine receptors and gephyrin scaffold proteins at inhibitory synapses. Biophysical Journal
Kostrz DN, Wayment-Steele HK, Wang J, et al. (2020) A Modular DNA Scaffold to Study Protein-Protein Interactions at Single-Molecule Resolution Biophysical Journal. 118: 187a
Niwa F, Patrizio A, Triller A, et al. (2019) cAMP-EPAC-Dependent Regulation of Gephyrin Phosphorylation and GABAR Trapping at Inhibitory Synapses. Iscience. 22: 453-465
Yang X, Specht CG. (2019) Subsynaptic Domains in Super-Resolution Microscopy: The Treachery of Images. Frontiers in Molecular Neuroscience. 12: 161
Specht CG. (2019) Fractional occupancy of synaptic binding sites and the molecular plasticity of inhibitory synapses. Neuropharmacology
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