Wei-Hsiang Huang, Ph.D.

2019- Neurology and Neurosurgery McGill University, Montreal, QC, Canada 
Neurodevelopmental Disorders
"Wei-Hsiang Huang"
Mean distance: 14.41 (cluster 11)
Cross-listing: BCM Tree

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Chang YT, Lee YJ, Haque M, et al. (2024) Comparative analyses of the Smith-Magenis syndrome protein RAI1 in mice and common marmoset monkeys. The Journal of Comparative Neurology. 532: e25589
Javed S, Chang YT, Cho Y, et al. (2023) Smith-Magenis syndrome protein RAI1 regulates body weight homeostasis through hypothalamic BDNF-producing neurons and neurotrophin downstream signalling. Elife. 12
Chang HC, Lee YJ, Javed S, et al. (2022) rAAV-CRISPRa therapy corrects Rai1 haploinsufficiency and rescues selective disease features in Smith-Magenis syndrome mice. The Journal of Biological Chemistry. 102728
Chang YT, Kowalczyk M, Fogerson PM, et al. (2022) Loss of enhances hippocampal excitability and epileptogenesis in mouse models of Smith-Magenis syndrome. Proceedings of the National Academy of Sciences of the United States of America. 119: e2210122119
Huang WH. (2022) Performing Single-Cell Clonal Analysis in the Mouse Brain Using Mosaic Analysis with Double Markers (MADM). Methods in Molecular Biology (Clifton, N.J.). 2515: 59-74
Javed S, Lee YJ, Xu J, et al. (2021) Temporal dissection of Rai1 function reveals brain-derived neurotrophic factor as a potential therapeutic target for Smith-Magenis syndrome. Human Molecular Genetics
Javed S, Selliah T, Lee YJ, et al. (2020) Dosage-sensitive genes in autism spectrum disorders: From neurobiology to therapy. Neuroscience and Biobehavioral Reviews
Luo L, Ambrozkiewicz MC, Benseler F, et al. (2020) Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors. Neuron
Huang WH, Wang DC, Allen WE, et al. (2018) Early adolescent Rai1 reactivation reverses transcriptional and social interaction deficits in a mouse model of Smith-Magenis syndrome. Proceedings of the National Academy of Sciences of the United States of America
Yeh SY, Huang WH, Wang W, et al. (2017) Respiratory Network Stability and Modulatory Response to Substance P Require Nalcn. Neuron
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