Andrea LeBlanc
Affiliations: | McGill University, Montreal, QC, Canada |
Area:
Neuroscience BiologyGoogle:
"Andrea LeBlanc"Mean distance: 106866
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Publications
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| Zhou L, Nho K, Haddad MG, et al. (2021) Rare CASP6N73T variant associated with hippocampal volume exhibits decreased proteolytic activity, synaptic transmission defect, and neurodegeneration. Scientific Reports. 11: 12695 |
| Flores J, Noël A, Foveau B, et al. (2020) Pre-symptomatic Caspase-1 inhibitor delays cognitive decline in a mouse model of Alzheimer disease and aging. Nature Communications. 11: 4571 |
| Zhou L, Flores J, Noël A, et al. (2019) Methylene blue inhibits Caspase-6 activity, and reverses Caspase-6-induced cognitive impairment and neuroinflammation in aged mice. Acta Neuropathologica Communications. 7: 210 |
| Tubeleviciute-Aydin A, Beautrait A, Lynham J, et al. (2019) Identification of Allosteric Inhibitors against Active Caspase-6. Scientific Reports. 9: 5504 |
| Foveau B, Correia AS, Hébert SS, et al. (2019) Stem Cell-Derived Neurons as Cellular Models of Sporadic Alzheimer's Disease. Journal of Alzheimer's Disease : Jad |
| Flores J, Noël A, Foveau B, et al. (2018) Caspase-1 inhibition alleviates cognitive impairment and neuropathology in an Alzheimer's disease mouse model. Nature Communications. 9: 3916 |
| Noël A, Zhou L, Foveau B, et al. (2018) Differential susceptibility of striatal, hippocampal and cortical neurons to Caspase-6. Cell Death and Differentiation |
| Victor KG, Heffron DS, Sokolowski JD, et al. (2017) Proteomic Identification of Synaptic Caspase Substrates. Synapse (New York, N.Y.) |
| Pakavathkumar P, Noël A, Lecrux C, et al. (2017) Caspase vinyl sulfone small molecule inhibitors prevent axonal degeneration in human neurons and reverse cognitive impairment in Caspase-6-overexpressing mice. Molecular Neurodegeneration. 12: 22 |
| Pakavathkumar P, Sharma G, Kaushal V, et al. (2015) Methylene Blue Inhibits Caspases by Oxidation of the Catalytic Cysteine. Scientific Reports. 5: 13730 |