Fen-Biao Gao

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
Neuroscience Biology
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"Fen-Biao Gao"
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Jack D. Keene grad student (Cell Biology Tree)
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Publications

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Dong D, Zhang Z, Li Y, et al. (2024) Poly-GR repeats associated with ALS/FTD gene impair translation elongation and induce a ribotoxic stress response in neurons. Science Signaling. 17: eadl1030
Halim DO, Krishnan G, Hass EP, et al. (2024) The exocyst subunit EXOC2 regulates the toxicity of expanded GGGGCC repeats in C9ORF72-ALS/FTD. Cell Reports. 43: 114375
Fang M, Deibler SK, Nana AL, et al. (2023) Loss of TDP-43 function contributes to genomic instability in amyotrophic lateral sclerosis. Frontiers in Neuroscience. 17: 1251228
Rojas F, Aguilar R, Almeida S, et al. (2023) Mature iPSC-derived astrocytes of an ALS/FTD patient carrying the TDP43 mutation display a mild reactive state and release polyP toxic to motoneurons. Frontiers in Cell and Developmental Biology. 11: 1226604
Lorenzini I, Alsop E, Levy J, et al. (2023) Moderate intrinsic phenotypic alterations in ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features. Frontiers in Cellular Neuroscience. 17: 1179796
Lee S, Jun YW, Linares GR, et al. (2023) Downregulation of Hsp90 and the antimicrobial peptide Mtk suppresses poly(GR)-induced neurotoxicity in C9ORF72-ALS/FTD. Neuron
Jun YW, Lee S, Ban BK, et al. (2023) Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis. Autophagy. 1-17
Hung ST, Linares GR, Chang WH, et al. (2023) PIKFYVE inhibition mitigates disease in models of diverse forms of ALS. Cell
Phillips HL, Dai H, Choi SY, et al. (2023) Dorsomedial prefrontal hypoexcitability underlies lost empathy in frontotemporal dementia. Neuron
Chen Y, Krishnan G, Parsi S, et al. (2022) The enhanced association between mutant CHMP2B and spastin is a novel pathological link between frontotemporal dementia and hereditary spastic paraplegias. Acta Neuropathologica Communications. 10: 169
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