Fen-Biao Gao - Publications

University of California, San Francisco, San Francisco, CA 
Neuroscience Biology

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lu Y, West RJH, Pons M, Sweeney ST, Gao FB. Ik2/TBK1 and Hook/Dynein, an adaptor complex for early endosome transport, are genetic modifiers of FTD-associated mutant CHMP2B toxicity in Drosophila. Scientific Reports. 10: 14221. PMID 32848189 DOI: 10.1038/s41598-020-71097-5  0.32
2020 Li S, Wu Z, Li Y, Tantray I, De Stefani D, Mattarei A, Krishnan G, Gao FB, Vogel H, Lu B. Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD. Cell Reports. 32: 107989. PMID 32755582 DOI: 10.1016/j.celrep.2020.107989  0.32
2016 Lopez-Gonzalez R, Lu Y, Gendron TF, Karydas A, Tran H, Yang D, Petrucelli L, Miller BL, Almeida S, Gao FB. Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons. Neuron. PMID 27720481 DOI: 10.1016/j.neuron.2016.09.015  0.32
2016 Lee JA, Yue Z, Gao FB. Autophagy in neurodegenerative diseases. Brain Research. 1649: 141-142. PMID 27712723 DOI: 10.1016/j.brainres.2016.09.030  1
2016 Biswas MH, Almeida S, Lopez-Gonzalez R, Mao W, Zhang Z, Karydas A, Geschwind MD, Biernat J, Mandelkow EM, Futai K, Miller BL, Gao FB. MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations. Stem Cell Reports. PMID 27594586 DOI: 10.1016/j.stemcr.2016.08.006  0.4
2016 Silva MC, Cheng C, Mair W, Almeida S, Fong H, Biswas MH, Zhang Z, Huang Y, Temple S, Coppola G, Geschwind DH, Karydas A, Miller BL, Kosik KS, Gao FB, et al. Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability. Stem Cell Reports. PMID 27594585 DOI: 10.1016/j.stemcr.2016.08.001  0.4
2016 Kramer NJ, Carlomagno Y, Zhang YJ, Almeida S, Cook CN, Gendron TF, Prudencio M, Van Blitterswijk M, Belzil V, Couthouis J, Paul JW, Goodman LD, Daughrity L, Chew J, Garrett A, ... ... Gao FB, et al. Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts. Science (New York, N.Y.). 353: 708-12. PMID 27516603 DOI: 10.1126/science.aaf7791  0.4
2015 Schweizer Burguete A, Almeida S, Gao FB, Kalb R, Akins MR, Bonini NM. GGGGCC microsatellite RNA is neuritically localized, induces branching defects, and perturbs transport granule function. Elife. 4. PMID 26650351 DOI: 10.7554/eLife.08881  0.4
2015 Tran H, Almeida S, Moore J, Gendron TF, Chalasani U, Lu Y, Du X, Nickerson JA, Petrucelli L, Weng Z, Gao FB. Differential Toxicity of Nuclear RNA Foci versus Dipeptide Repeat Proteins in a Drosophila Model of C9ORF72 FTD/ALS. Neuron. 87: 1207-14. PMID 26402604 DOI: 10.1016/j.neuron.2015.09.015  0.4
2015 Freibaum BD, Lu Y, Lopez-Gonzalez R, Kim NC, Almeida S, Lee KH, Badders N, Valentine M, Miller BL, Wong PC, Petrucelli L, Kim HJ, Gao FB, Taylor JP. GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport. Nature. 525: 129-33. PMID 26308899 DOI: 10.1038/nature14974  0.4
2015 Yang D, Abdallah A, Li Z, Lu Y, Almeida S, Gao FB. FTD/ALS-associated poly(GR) protein impairs the Notch pathway and is recruited by poly(GA) into cytoplasmic inclusions. Acta Neuropathologica. PMID 26031661 DOI: 10.1007/s00401-015-1448-6  0.4
2015 Yuva-Aydemir Y, Xu XL, Aydemir O, Gascon E, Sayin S, Zhou W, Hong Y, Gao FB. Downregulation of the Host Gene jigr1 by miR-92 Is Essential for Neuroblast Self-Renewal in Drosophila. Plos Genetics. 11: e1005264. PMID 26000445 DOI: 10.1371/journal.pgen.1005264  0.4
2015 West RJ, Lu Y, Marie B, Gao FB, Sweeney ST. Rab8, POSH, and TAK1 regulate synaptic growth in a Drosophila model of frontotemporal dementia. The Journal of Cell Biology. 208: 931-47. PMID 25800055 DOI: 10.1083/jcb.201404066  0.32
2014 Gascon E, Lynch K, Ruan H, Almeida S, Verheyden JM, Seeley WW, Dickson DW, Petrucelli L, Sun D, Jiao J, Zhou H, Jakovcevski M, Akbarian S, Yao WD, Gao FB. Alterations in microRNA-124 and AMPA receptors contribute to social behavioral deficits in frontotemporal dementia. Nature Medicine. 20: 1444-51. PMID 25401692 DOI: 10.1038/nm.3717  0.4
2014 Gao FB, Taylor JP. RNA metabolism in neurological disease. Brain Research. 1584: 1-2. PMID 25248315 DOI: 10.1016/j.brainres.2014.09.011  0.4
2014 Simkin AT, Bailey JA, Gao FB, Jensen JD. Inferring the evolutionary history of primate microRNA binding sites: overcoming motif counting biases. Molecular Biology and Evolution. 31: 1894-901. PMID 24723422 DOI: 10.1093/molbev/msu129  0.4
2014 Lee WC, Almeida S, Prudencio M, Caulfield TR, Zhang YJ, Tay WM, Bauer PO, Chew J, Sasaguri H, Jansen-West KR, Gendron TF, Stetler CT, Finch N, Mackenzie IR, Rademakers R, ... Gao FB, et al. Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency. Human Molecular Genetics. 23: 1467-78. PMID 24163244 DOI: 10.1093/hmg/ddt534  0.4
2014 Cheruiyot A, Lee JA, Gao FB, Ahmad ST. Expression of mutant CHMP2B, an ESCRT-III component involved in frontotemporal dementia, causes eye deformities due to Notch misregulation in Drosophila. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 667-75. PMID 24158394 DOI: 10.1096/fj.13-234138  1
2013 Zhang Z, Almeida S, Lu Y, Nishimura AL, Peng L, Sun D, Wu B, Karydas AM, Tartaglia MC, Fong JC, Miller BL, Farese RV, Moore MJ, Shaw CE, Gao FB. Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations. Plos One. 8: e76055. PMID 24143176 DOI: 10.1371/journal.pone.0076055  0.32
2013 Lu Y, Zhang Z, Sun D, Sweeney ST, Gao FB. Syntaxin 13, a genetic modifier of mutant CHMP2B in frontotemporal dementia, is required for autophagosome maturation. Molecular Cell. 52: 264-71. PMID 24095276 DOI: 10.1016/j.molcel.2013.08.041  0.32
2013 Almeida S, Gascon E, Tran H, Chou HJ, Gendron TF, Degroot S, Tapper AR, Sellier C, Charlet-Berguerand N, Karydas A, Seeley WW, Boxer AL, Petrucelli L, Miller BL, Gao FB. Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons. Acta Neuropathologica. 126: 385-99. PMID 23836290 DOI: 10.1007/s00401-013-1149-y  0.4
2013 Filiano AJ, Martens LH, Young AH, Warmus BA, Zhou P, Diaz-Ramirez G, Jiao J, Zhang Z, Huang EJ, Gao FB, Farese RV, Roberson ED. Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5352-61. PMID 23516300 DOI: 10.1523/JNEUROSCI.6103-11.2013  0.4
2013 Boxer AL, Gold M, Huey E, Hu WT, Rosen H, Kramer J, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, et al. The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: the next therapeutic frontier). Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 189-98. PMID 23062850 DOI: 10.1016/j.jalz.2012.03.003  0.4
2013 Boxer AL, Gold M, Huey E, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, et al. Frontotemporal degeneration, the next therapeutic frontier: molecules and animal models for frontotemporal degeneration drug development. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 176-88. PMID 23043900 DOI: 10.1016/j.jalz.2012.03.002  0.4
2013 Li Z, Lu Y, Xu XL, Gao FB. The FTD/ALS-associated RNA-binding protein TDP-43 regulates the robustness of neuronal specification through microRNA-9a in Drosophila. Human Molecular Genetics. 22: 218-25. PMID 23042786 DOI: 10.1093/hmg/dds420  0.32
2012 Almeida S, Delaloy C, Liu L, Gao FB. Protocols for investigating microRNA functions in human neural progenitor cells. Methods in Molecular Biology (Clifton, N.J.). 916: 387-402. PMID 22914955 DOI: 10.1007/978-1-61779-980-8_28  0.4
2012 González-Pérez P, Lu Y, Chian RJ, Sapp PC, Tanzi RE, Bertram L, McKenna-Yasek D, Gao FB, Brown RH. Association of UBQLN1 mutation with Brown-Vialetto-Van Laere syndrome but not typical ALS. Neurobiology of Disease. 48: 391-8. PMID 22766032 DOI: 10.1016/j.nbd.2012.06.018  0.4
2012 Gao FB, Taylor JP. RNA-binding proteins in neurological disease. Brain Research. 1462: 1-2. PMID 22682432 DOI: 10.1016/j.brainres.2012.05.038  0.4
2012 Lee JA, Gao FB. Neuronal Functions of ESCRTs. Experimental Neurobiology. 21: 9-15. PMID 22438674 DOI: 10.5607/en.2012.21.1.9  1
2012 Huang YJ, Wang H, Gao FB, Li M, Yang H, Wang B, Tai PC. Fluorescein analogues inhibit SecA ATPase: the first sub-micromolar inhibitor of bacterial protein translocation. Chemmedchem. 7: 571-7. PMID 22354575 DOI: 10.1002/cmdc.201100594  0.4
2012 Sun K, Westholm JO, Tsurudome K, Hagen JW, Lu Y, Kohwi M, Betel D, Gao FB, Haghighi AP, Doe CQ, Lai EC. Neurophysiological defects and neuronal gene deregulation in Drosophila mir-124 mutants. Plos Genetics. 8: e1002515. PMID 22347817 DOI: 10.1371/journal.pgen.1002515  0.4
2011 Lee JA, Liu L, Javier R, Kreitzer AC, Delaloy C, Gao FB. ESCRT-III subunits Snf7-1 and Snf7-2 differentially regulate transmembrane cargos in hESC-derived human neurons. Molecular Brain. 4: 37. PMID 21975012 DOI: 10.1186/1756-6606-4-37  0.4
2011 Xu XL, Zong R, Li Z, Biswas MH, Fang Z, Nelson DL, Gao FB. FXR1P but not FMRP regulates the levels of mammalian brain-specific microRNA-9 and microRNA-124. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 13705-9. PMID 21957233 DOI: 10.1523/JNEUROSCI.2827-11.2011  0.4
2011 Kuo TC, Chen CT, Baron D, Onder TT, Loewer S, Almeida S, Weismann CM, Xu P, Houghton JM, Gao FB, Daley GQ, Doxsey S. Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity. Nature Cell Biology. 13: 1214-23. PMID 21909099 DOI: 10.1038/ncb2332  0.4
2011 Cenik B, Sephton CF, Dewey CM, Xian X, Wei S, Yu K, Niu W, Coppola G, Coughlin SE, Lee SE, Dries DR, Almeida S, Geschwind DH, Gao FB, Miller BL, et al. Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia. The Journal of Biological Chemistry. 286: 16101-8. PMID 21454553 DOI: 10.1074/jbc.M110.193433  0.4
2010 Delaloy C, Gao FB. A new role for microRNA-9 in human neural progenitor cells. Cell Cycle (Georgetown, Tex.). 9: 2913-4. PMID 20676037 DOI: 10.4161/cc.9.15.12699  0.4
2010 Delaloy C, Liu L, Lee JA, Su H, Shen F, Yang GY, Young WL, Ivey KN, Gao FB. MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors. Cell Stem Cell. 6: 323-35. PMID 20362537 DOI: 10.1016/j.stem.2010.02.015  1
2010 Gao FB. Context-dependent functions of specific microRNAs in neuronal development Neural Development. 5. DOI: 10.1186/1749-8104-5-25  0.4
2009 Lu Y, Ferris J, Gao FB. Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching. Molecular Brain. 2: 30. PMID 19781077 DOI: 10.1186/1756-6606-2-30  0.32
2009 Lee JA, Liu L, Gao FB. Autophagy defects contribute to neurodegeneration induced by dysfunctional ESCRT-III. Autophagy. 5: 1070-2. PMID 19738424 DOI: 10.4161/auto.5.7.9823  1
2009 Ahmad ST, Sweeney ST, Lee JA, Sweeney NT, Gao FB. Genetic screen identifies serpin5 as a regulator of the toll pathway and CHMP2B toxicity associated with frontotemporal dementia. Proceedings of the National Academy of Sciences of the United States of America. 106: 12168-73. PMID 19581577 DOI: 10.1073/pnas.0903134106  0.6
2009 Lee JA, Gao FB. Inhibition of autophagy induction delays neuronal cell loss caused by dysfunctional ESCRT-III in frontotemporal dementia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8506-11. PMID 19571141 DOI: 10.1523/JNEUROSCI.0924-09.2009  1
2009 Lu Y, Wang F, Li Y, Ferris J, Lee JA, Gao FB. The Drosophila homologue of the Angelman syndrome ubiquitin ligase regulates the formation of terminal dendritic branches. Human Molecular Genetics. 18: 454-62. PMID 18996915 DOI: 10.1093/hmg/ddn373  1
2008 Lee JA, Gao FB. ESCRT, autophagy, and frontotemporal dementia. Bmb Reports. 41: 827-32. PMID 19123971 DOI: 10.5483/BMBRep.2008.41.12.827  1
2008 Xu XL, Li Y, Wang F, Gao FB. The steady-state level of the nervous-system-specific microRNA-124a is regulated by dFMR1 in Drosophila. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11883-9. PMID 19005053 DOI: 10.1523/JNEUROSCI.4114-08.2008  0.32
2008 Delaloy C, Gao FB. microRNA-9 multitasking near organizing centers. Nature Neuroscience. 11: 625-6. PMID 18506136 DOI: 10.1038/nn0608-625  0.4
2008 Lee JA, Gao FB. Regulation of Abeta pathology by beclin 1: a protective role for autophagy? The Journal of Clinical Investigation. 118: 2015-8. PMID 18497881 DOI: 10.1172/JCI35662  1
2008 Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, ... ... Gao FB, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy. 4: 151-75. PMID 18188003 DOI: 10.4161/auto.5338  0.4
2008 Lee JA, Gao FB. Roles of ESCRT in autophagy-associated neurodegeneration. Autophagy. 4: 230-2. PMID 18094607 DOI: 10.4161/auto.5384  1
2007 Gao FB. Molecular and cellular mechanisms of dendritic morphogenesis Current Opinion in Neurobiology. 17: 525-532. PMID 17933513 DOI: 10.1016/j.conb.2007.08.004  0.4
2007 Lee JA, Beigneux A, Ahmad ST, Young SG, Gao FB. ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration. Current Biology : Cb. 17: 1561-7. PMID 17683935 DOI: 10.1016/j.cub.2007.07.029  1
2006 Li Y, Wang F, Lee JA, Gao FB. MicroRNA-9a ensures the precise specification of sensory organ precursors in Drosophila. Genes & Development. 20: 2793-805. PMID 17015424 DOI: 10.1101/gad.1466306  1
2006 Sweeney NT, Brenman JE, Jan YN, Gao FB. The coiled-coil protein shrub controls neuronal morphogenesis in Drosophila. Current Biology : Cb. 16: 1006-11. PMID 16713958 DOI: 10.1016/j.cub.2006.03.067  0.4
2005 Li W, Li Y, Gao FB. Abelson, enabled, and p120 catenin exert distinct effects on dendritic morphogenesis in Drosophila. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 234: 512-22. PMID 16003769 DOI: 10.1002/dvdy.20496  0.32
2004 Li W, Wang F, Menut L, Gao FB. BTB/POZ-zinc finger protein abrupt suppresses dendritic branching in a neuronal subtype-specific and dosage-dependent manner. Neuron. 43: 823-34. PMID 15363393 DOI: 10.1016/j.neuron.2004.08.040  0.32
2004 Xu K, Bogert BA, Li W, Su K, Lee A, Gao FB. The fragile X-related gene affects the crawling behavior of Drosophila larvae by regulating the mRNA level of the DEG/ENaC protein pickpocket1. Current Biology : Cb. 14: 1025-34. PMID 15202995 DOI: 10.1016/j.cub.2004.05.055  0.4
2003 Lee A, Li W, Xu K, Bogert BA, Su K, Gao FB. Control of dendritic development by the Drosophila fragile X-related gene involves the small GTPase Rac1. Development (Cambridge, England). 130: 5543-52. PMID 14530299 DOI: 10.1242/dev.00792  0.4
2003 Gao FB, Bogert BA. Genetic control of dendritic morphogenesis in Drosophila. Trends in Neurosciences. 26: 262-8. PMID 12744843 DOI: 10.1016/S0166-2236(03)00078-X  0.4
2002 Gao FB. Understanding fragile X syndrome: Insights from retarded flies Neuron. 34: 859-862. PMID 12086633 DOI: 10.1016/S0896-6273(02)00740-7  0.4
2002 Sweeney NT, Li W, Gao FB. Genetic manipulation of single neurons in vivo reveals specific roles of flamingo in neuronal morphogenesis. Developmental Biology. 247: 76-88. PMID 12074553 DOI: 10.1006/dbio.2002.0702  0.4
2002 Tokumoto YM, Apperly JA, Gao FB, Raff MC. Posttranscriptional regulation of p18 and p27 Cdk inhibitor proteins and the timing of oligodendrocyte differentiation. Developmental Biology. 245: 224-34. PMID 11969268 DOI: 10.1006/dbio.2002.0626  0.4
2000 Gao FB, Kohwi M, Brenman JE, Jan LY, Jan YN. Control of dendritic field formation in Drosophila: the roles of flamingo and competition between homologous neurons. Neuron. 28: 91-101. PMID 11086986 DOI: 10.1016/S0896-6273(00)00088-X  0.4
1997 Gao FB, Raff M. Cell size control and a cell-intrinsic maturation program in proliferating oligodendrocyte precursor cells Journal of Cell Biology. 138: 1367-1377. PMID 9298991 DOI: 10.1083/jcb.138.6.1367  0.4
1997 Gao FB, Durand B, Raff M. Oligodendrocyte precursor cells count time but not cell divisions before differentiation Current Biology. 7: 152-155. PMID 9016704 DOI: 10.1016/S0960-9822(06)00060-1  0.4
Show low-probability matches.