Javier E. Irazoqui

Affiliations: 
2008-2017 Massachusetts General Hospital Harvard Medical School, Boston, MA, United States 
 2017- Microbiology and Physiological Systems University of Massachussetts Medical School, Worcester, MA, United States 
Area:
Host-microbe interactions, caenorhabditis elegans, staphylococcus aureus, bacterial pathogenesis
Google:
"Javier Elbio Irazoqui"
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Publications

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Gonzalez X, Irazoqui JE. (2023) Distinct members of the CeMbio reference microbiota exert cryptic virulence and infection protection. Biorxiv : the Preprint Server For Biology
Goswamy D, Gonzalez X, Labed SA, et al. (2023) orphan nuclear receptor NHR-42 represses innate immunity and promotes lipid loss downstream of HLH-30/TFEB. Frontiers in Immunology. 14: 1094145
Wani KA, Goswamy D, Taubert S, et al. (2021) NHR-49/PPAR-α and HLH-30/TFEB cooperate for host defense via a flavin-containing monooxygenase. Elife. 10
Najibi M, Honwad HH, Moreau JA, et al. (2021) A NOVEL NOX/PHOX-CD38-NAADP-TFEB AXIS IMPORTANT FOR MACROPHAGE ACTIVATION DURING BACTERIAL PHAGOCYTOSIS. Autophagy. 1-18
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, et al. (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382
Goswamy D, Irazoqui JE. (2020) A unifying hypothesis on the central role of reactive oxygen species in bacterial pathogenesis and host defense in C. elegans. Current Opinion in Immunology. 68: 9-20
Irazoqui JE. (2020) Key Roles of MiT Transcription Factors in Innate Immunity and Inflammation. Trends in Immunology. 41: 157-171
Wani KA, Goswamy D, Irazoqui JE. (2019) Nervous system control of intestinal host defense in C. elegans. Current Opinion in Neurobiology. 62: 1-9
Wani KA, Goswamy D, Irazoqui JE. (2019) A Nutrition-Longevity Tradeoff Enforced by Innate Immunity. Molecular Cell. 74: 864-865
Labed SA, Wani KA, Jagadeesan S, et al. (2019) Intestinal Epithelial Wnt Signaling Mediates Acetylcholine-Triggered Host Defense against Infection. Immunity. 48: 963-978.e3
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