Courtney Thaxton, Ph.D.

Affiliations: 
2007 University of Central Florida, Orlando, FL, United States 
Area:
Molecular Biology, Neuroscience Biology
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"Courtney Thaxton"
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Cristina Fernandez-Valle grad student 2007 University of Central Florida
 (Mechanisms promoting phosphorylation of the nf2 tumor supressor and its effects on Schwann cell development.)
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Publications

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Buttermore ED, Thaxton CL, Bhat MA. (2013) Organization and maintenance of molecular domains in myelinated axons. Journal of Neuroscience Research. 91: 603-22
Thaxton C, Pillai AM, Pribisko AL, et al. (2011) Nodes of Ranvier act as barriers to restrict invasion of flanking paranodal domains in myelinated axons. Neuron. 69: 244-57
Thaxton C, Bott M, Walker B, et al. (2011) Schwannomin/merlin promotes Schwann cell elongation and influences myelin segment length. Molecular and Cellular Neurosciences. 47: 1-9
Thaxton C, Pillai AM, Pribisko AL, et al. (2010) In vivo deletion of immunoglobulin domains 5 and 6 in neurofascin (Nfasc) reveals domain-specific requirements in myelinated axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 4868-76
Thaxton C, Bhat MA. (2009) Myelination and regional domain differentiation of the axon. Results and Problems in Cell Differentiation. 48: 1-28
Pillai AM, Thaxton C, Pribisko AL, et al. (2009) Spatiotemporal ablation of myelinating glia-specific neurofascin (Nfasc NF155) in mice reveals gradual loss of paranodal axoglial junctions and concomitant disorganization of axonal domains. Journal of Neuroscience Research. 87: 1773-93
Thaxton C, Lopera J, Bott M, et al. (2008) Neuregulin and laminin stimulate phosphorylation of the NF2 tumor suppressor in Schwann cells by distinct protein kinase A and p21-activated kinase-dependent pathways. Oncogene. 27: 2705-15
Thaxton C, Lopera J, Bott M, et al. (2007) Phosphorylation of the NF2 tumor suppressor in Schwann cells is mediated by Cdc42-Pak and requires paxillin binding. Molecular and Cellular Neurosciences. 34: 231-42
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