Ryoko Hirakawa, Ph.D.
Affiliations: | 2009 | University of the Pacific, Stockton, CA, United States |
Area:
Pharmacology, Toxicology, Neuroscience BiologyGoogle:
"Ryoko Hirakawa"Mean distance: 42746.4
Parents
Sign in to add mentor| Robert F. Halliwell | grad student | 2009 | University of the Pacific | |
| (Electrophysiological studies of the interaction between ciprofloxacin and biphenylacetic acid at neuronal receptors and ion channels.) | ||||
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Publications
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| El-Bizri N, Xie C, Liu L, et al. (2017) Eleclazine exhibits enhanced selectivity for LQT3-associated late INa. Heart Rhythm |
| Zablocki JA, Elzein E, Li X, et al. (2016) Discovery of Dihydrobenzoxazepinone (GS-6615) Late Sodium Current Inhibitor (Late INai), a Phase II Agent with Demonstrated Preclinical Anti-Ischemic and Antiarrhythmic Properties. Journal of Medicinal Chemistry |
| Chi L, Belardinelli L, Zeng A, et al. (2016) Inhibition of late Na current, a novel target to improve diastolic function and electrical abnormalities in Dahl salt-sensitive rats. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00863.2015 |
| Kornyeyev D, El-Bizri N, Hirakawa R, et al. (2015) Contribution of the late sodium current to intracellular sodium and calcium overload in rabbit ventricular myocytes treated by anemone toxin. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00520.2015 |
| Sahdeo S, Wallace T, Hirakawa R, et al. (2014) Characterization of RO5126946, a Novel α7 nicotinic acetylcholine receptor-positive allosteric modulator. The Journal of Pharmacology and Experimental Therapeutics. 350: 455-68 |
| Kahlig KM, Hirakawa R, Liu L, et al. (2014) Ranolazine reduces neuronal excitability by interacting with inactivated states of brain sodium channels. Molecular Pharmacology. 85: 162-74 |
| Hirakawa R, Belardinelli L, Rajamani S. (2014) Block of Na+ Currents and Suppression of Action Potentials in Cultured Hippocampal Neurons by Gs-458967 Biophysical Journal. 106 |
| Belardinelli L, Liu G, Smith-Maxwell C, et al. (2013) A novel, potent, and selective inhibitor of cardiac late sodium current suppresses experimental arrhythmias. The Journal of Pharmacology and Experimental Therapeutics. 344: 23-32 |
| Hirakawa R, El-Bizri N, Shryock JC, et al. (2012) Block of Na+ currents and suppression of action potentials in embryonic rat dorsal root ganglion neurons by ranolazine. Neuropharmacology. 62: 2251-60 |
| Hirakawa R, Kahlig KM, Shan M, et al. (2012) Ranolazine Reduces Central Neuron Excitability by Slowly Interacting with NaV Channels Biophysical Journal. 102: 3-3 |