Michael S. Cohen, Ph.D.

Oregon Health and Sciences University Oregon Health and Science University, Portland, OR 
Poly-ADP ribosylation, PARPs, cancer, neuroscience
"Michael Cohen"
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Vermehren-Schmaedick A, Huang JY, Levinson M, et al. (2021) Characterization of PARP6 Function in Knockout Mice and Patients with Developmental Delay. Cells. 10
Cohen MS. (2020) Interplay between compartmentalized NAD synthesis and consumption: a focus on the PARP family. Genes & Development
Morgan RK, Kirby IT, Vermehren-Schmaedick A, et al. (2019) Rational Design of Cell-Active Inhibitors of PARP10. Acs Medicinal Chemistry Letters. 10: 74-79
Carter-O'Connell I, Vermehren Schmaedick A, Jin H, et al. (2018) Combining Chemical Genetics with Proximity-Dependent Labeling Reveals Cellular Targets of PARP14. Acs Chemical Biology
Kirby IT, Cohen MS. (2018) Small-Molecule Inhibitors of PARPs: From Tools for Investigating ADP-Ribosylation to Therapeutics. Current Topics in Microbiology and Immunology
Kirby IT, Morgan RK, Cohen MS. (2018) A Simple, Sensitive, and Generalizable Plate Assay for Screening PARP Inhibitors. Methods in Molecular Biology (Clifton, N.J.). 1813: 245-252
Cohen MS, Chang P. (2018) Insights into the biogenesis, function, and regulation of ADP-ribosylation. Nature Chemical Biology. 14: 236-243
Morgan RK, Cohen MS. (2017) Detecting Protein ADP-Ribosylation Using a Clickable Aminooxy Probe. Methods in Molecular Biology (Clifton, N.J.). 1608: 71-77
Thorsell AG, Ekblad T, Karlberg T, et al. (2016) Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors. Journal of Medicinal Chemistry
Carter-O'Connell I, Jin H, Morgan RK, et al. (2016) Identifying Family-Member-Specific Targets of Mono-ARTDs by Using a Chemical Genetics Approach. Cell Reports
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