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Michael S. Cohen, Ph.D. - Publications

Affiliations: 
Oregon Health and Sciences University Oregon Health and Science University, Portland, OR 
Area:
Poly-ADP ribosylation, PARPs, cancer, neuroscience
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Vermehren-Schmaedick A, Huang JY, Levinson M, Pomaville MB, Reed S, Bellus GA, Gilbert F, Keren B, Heron D, Haye D, Janello C, Makowski C, Danhauser K, Fedorov LM, Haack TB, ... ... Cohen MS, et al. Characterization of PARP6 Function in Knockout Mice and Patients with Developmental Delay. Cells. 10. PMID 34067418 DOI: 10.3390/cells10061289  0.407
2020 Cohen MS. Interplay between compartmentalized NAD synthesis and consumption: a focus on the PARP family. Genes & Development. PMID 32029457 DOI: 10.1101/Gad.335109.119  0.305
2019 Morgan RK, Kirby IT, Vermehren-Schmaedick A, Rodriguez K, Cohen MS. Rational Design of Cell-Active Inhibitors of PARP10. Acs Medicinal Chemistry Letters. 10: 74-79. PMID 30655950 DOI: 10.1021/Acsmedchemlett.8B00429  0.317
2018 Carter-O'Connell I, Vermehren Schmaedick A, Jin H, Morgan RK, David LL, Cohen MS. Combining Chemical Genetics with Proximity-Dependent Labeling Reveals Cellular Targets of PARP14. Acs Chemical Biology. PMID 30247868 DOI: 10.1021/Acschembio.8B00567  0.335
2018 Kirby IT, Cohen MS. Small-Molecule Inhibitors of PARPs: From Tools for Investigating ADP-Ribosylation to Therapeutics. Current Topics in Microbiology and Immunology. PMID 30242511 DOI: 10.1007/82_2018_137  0.31
2018 Kirby IT, Morgan RK, Cohen MS. A Simple, Sensitive, and Generalizable Plate Assay for Screening PARP Inhibitors. Methods in Molecular Biology (Clifton, N.J.). 1813: 245-252. PMID 30097873 DOI: 10.1007/978-1-4939-8588-3_17  0.325
2018 Cohen MS, Chang P. Insights into the biogenesis, function, and regulation of ADP-ribosylation. Nature Chemical Biology. 14: 236-243. PMID 29443986 DOI: 10.1038/Nchembio.2568  0.31
2016 Thorsell AG, Ekblad T, Karlberg T, Löw M, Pinto AF, Trésaugues L, Moche M, Cohen MS, Schüler H. Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors. Journal of Medicinal Chemistry. PMID 28001384 DOI: 10.1021/Acs.Jmedchem.6B00990  0.302
2016 Carter-O'Connell I, Jin H, Morgan RK, Zaja R, David LL, Ahel I, Cohen MS. Identifying Family-Member-Specific Targets of Mono-ARTDs by Using a Chemical Genetics Approach. Cell Reports. PMID 26774478 DOI: 10.1016/J.Celrep.2015.12.045  0.316
2016 Huang JY, Wang K, Vermehren-Schmaedick A, Adelman JP, Cohen MS. PARP6 is a Regulator of Hippocampal Dendritic Morphogenesis. Scientific Reports. 6: 18512. PMID 26725726 DOI: 10.1038/Srep18512  0.474
2015 Carter-O'Connell I, Cohen MS. Identifying Direct Protein Targets of Poly-ADP-Ribose Polymerases (PARPs) Using Engineered PARP Variants-Orthogonal Nicotinamide Adenine Dinucleotide (NAD+) Analog Pairs. Current Protocols in Chemical Biology. 7: 121-39. PMID 26344237 DOI: 10.1002/9780470559277.Ch140259  0.343
2015 Morgan RK, Carter-O'Connell I, Cohen MS. Selective inhibition of PARP10 using a chemical genetics strategy. Bioorganic & Medicinal Chemistry Letters. 25: 4770-3. PMID 26231158 DOI: 10.1016/J.Bmcl.2015.07.033  0.315
2014 Carter-O'Connell I, Jin H, Morgan RK, David LL, Cohen MS. Engineering the substrate specificity of ADP-ribosyltransferases for identifying direct protein targets. Journal of the American Chemical Society. 136: 5201-4. PMID 24641686 DOI: 10.1021/Ja412897A  0.324
2012 Serafimova IM, Pufall MA, Krishnan S, Duda K, Cohen MS, Maglathlin RL, McFarland JM, Miller RM, Frödin M, Taunton J. Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles. Nature Chemical Biology. 8: 471-6. PMID 22466421 DOI: 10.1038/Nchembio.925  0.326
2009 Chaturvedi D, Cohen MS, Taunton J, Patel TB. The PKARIalpha subunit of protein kinase A modulates the activation of p90RSK1 and its function. The Journal of Biological Chemistry. 284: 23670-81. PMID 19570980 DOI: 10.1074/Jbc.M109.032813  0.311
2008 Visintin C, Tomson BN, Rahal R, Paulson J, Cohen M, Taunton J, Amon A, Visintin R. APC/C-Cdh1-mediated degradation of the Polo kinase Cdc5 promotes the return of Cdc14 into the nucleolus. Genes & Development. 22: 79-90. PMID 18172166 DOI: 10.1101/Gad.1601308  0.323
2007 Snead JL, Sullivan M, Lowery DM, Cohen MS, Zhang C, Randle DH, Taunton J, Yaffe MB, Morgan DO, Shokat KM. A coupled chemical-genetic and bioinformatic approach to Polo-like kinase pathway exploration. Chemistry & Biology. 14: 1261-72. PMID 18022565 DOI: 10.1016/J.Chembiol.2007.09.011  0.338
2007 Kang S, Dong S, Gu TL, Guo A, Cohen MS, Lonial S, Khoury HJ, Fabbro D, Gilliland DG, Bergsagel PL, Taunton J, Polakiewicz RD, Chen J. FGFR3 activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway. Cancer Cell. 12: 201-14. PMID 17785202 DOI: 10.1016/J.CCR.2007.08.003  0.321
2007 Roux PP, Shahbazian D, Vu H, Holz MK, Cohen MS, Taunton J, Sonenberg N, Blenis J. RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation. The Journal of Biological Chemistry. 282: 14056-64. PMID 17360704 DOI: 10.1074/Jbc.M700906200  0.302
2007 Cohen MS, Hadjivassiliou H, Taunton J. A clickable inhibitor reveals context-dependent autoactivation of p90 RSK. Nature Chemical Biology. 3: 156-60. PMID 17259979 DOI: 10.1038/Nchembio859  0.339
2007 Hetzer C, Bisgrove D, Cohen MS, Pedal A, Kaehlcke K, Speyerer A, Bartscherer K, Taunton J, Ott M. Recruitment and activation of RSK2 by HIV-1 Tat. Plos One. 2: e151. PMID 17225856 DOI: 10.1371/Journal.Pone.0000151  0.331
2007 Cuello F, Snabaitis AK, Cohen MS, Taunton J, Avkiran M. Evidence for direct regulation of myocardial Na+/H+ exchanger isoform 1 phosphorylation and activity by 90-kDa ribosomal S6 kinase (RSK): effects of the novel and specific RSK inhibitor fmk on responses to alpha1-adrenergic stimulation. Molecular Pharmacology. 71: 799-806. PMID 17142297 DOI: 10.1124/Mol.106.029900  0.3
2007 Kang S, Dong S, Gu T, Guo A, Cohen MS, Lonial S, Bergsagel PL, Taunton J, Polakiewicz RD, Chen J. p90RSK2 as a Therapeutic Target in Treatment of FGFR3-Expressing t(4;14) Multiple Myeloma. Blood. 110: 253-253. DOI: 10.1182/Blood.V110.11.253.253  0.335
2006 Shahbazian D, Roux PP, Mieulet V, Cohen MS, Raught B, Taunton J, Hershey JW, Blenis J, Pende M, Sonenberg N. The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity. The Embo Journal. 25: 2781-91. PMID 16763566 DOI: 10.1038/Sj.Emboj.7601166  0.307
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