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Gilbert J. Mannering

Affiliations: 
Pharmacology University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
drug metabolism, biochemical toxicology
Website:
http://www.aspet.org/uploadedFiles/Publications/Journal_Search/v46n2_6_04.pdf
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"Gilbert Mannering"
Bio:

(1917 - 2004)

Gilbert Mannering, Professor of Pharmacology at the University of Minnesota from 1962 to 1987, died of natural causes, March 20, 2004. A man of seemingly endless energy (he toured the Amazon basin at the age of 83!) and an unbridled zest for life, he was one of the fortunate few who enjoyed an extraordinarily hardy constitution and was rarely, if ever, ill until late in life when he was diagnosed with type 2 diabetes, and very late in life when he endured vascular dementia. Professor Mannering had been a regular/emeritus member of the American Society of Pharmacology and Experimental Therapeutics since 1956. A memorial service celebrating his life was held on April 3, 2004, at the University Club (his favorite local haunt), St. Paul, Minnesota.
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Mean distance: 16.53 (cluster 6)
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Cross-listing: Chemistry Tree

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Parents

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Conrad (Arnold) Elvehjem grad student 1944 UW Madison (Chemistry Tree)
 (Newer dietary essentials required by the guinea pig)

Children

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Akira E. Takemori grad student 1958 UW Madison
Thomas R. Tephly grad student 1962 UW Madison (Chemistry Tree)

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Publications

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Kuwahara SK, Mannering GJ. (1993) Effects of interferon, polyriboinosinic acid--polyribocytidilic acid and steroids on the cytochrome P450 system of cultured primary mouse hepatocytes. Pharmacology & Toxicology. 72: 199-204
Iba MM, Mannering GJ. (1987) NADPH- and linoleic acid hydroperoxide-induced lipid peroxidation and destruction of cytochrome P-450 in hepatic microsomes. Biochemical Pharmacology. 36: 1447-55
Kuwahara S, Mannering GJ. (1985) Evidence for a predominantly NADH-dependent O-dealkylating system in rat hepatic microsomes. Biochemical Pharmacology. 34: 4215-28
Gurumurthy P, Mannering GJ. (1985) Membrane bound cytochrome P-450 determines the optimal temperatures of NADPH-cytochrome P-450 reductase and cytochrome P-450-linked monooxygenase reactions in rat and trout hepatic microsomes. Biochemical and Biophysical Research Communications. 127: 571-7
Robbins MS, Mannering GJ. (1984) Effects of the interferon inducing agents tilorone and polyriboinosinic acid . polyribocytidylic acid (poly IC) on the hepatic monooxygenase systems of pregnant and fetal rats. Biochemical Pharmacology. 33: 1213-22
Schwen RJ, Mannering GJ. (1982) Hepatic cytochrome P-450-dependent monooxygenase systems of the trout, frog and snake--III. Induction. Comparative Biochemistry and Physiology. B, Comparative Biochemistry. 71: 445-53
Schwen RJ, Mannering GJ. (1982) Hepatic cytochrome P-450-dependent monooxygenase systems of the trout, frog and snake--II. Monooxygenase activities. Comparative Biochemistry and Physiology. B, Comparative Biochemistry. 71: 437-43
Schwen RJ, Mannering GJ. (1982) Hepatic cytochrome P-450-dependent monooxygenase systems of the trout, frog and snake--I. Components. Comparative Biochemistry and Physiology. B, Comparative Biochemistry. 71: 431-6
Deloria LB, Mannering GJ. (1982) Sequential administrations of polyriboinosinic acid and polyribocytidylic acid induce interferon and depress the hepatic cytochrome P-450-dependent monooxygenase system. Biochemical and Biophysical Research Communications. 106: 947-52
Mannering GJ, Renton KW, el Azhary R, et al. (1980) Effects of interferon-inducing agents on hepatic cytochrome P-450 drug metabolizing systems. Annals of the New York Academy of Sciences. 350: 314-31
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