Ralph J. Bernacki

Affiliations: 
State University of New York, Buffalo, Buffalo, NY, United States 
Area:
Pharmacology, Oncology, Cell Biology
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"Ralph Bernacki"
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Publications

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Kuznetsova L, Sun L, Chen J, et al. (2012) Synthesis and Biological Evaluation of Novel 3'-Difluorovinyl Taxoids. Journal of Fluorine Chemistry. 143: 177-188
Sajjad M, Riaz U, Yao R, et al. (2012) Investigation of 3'-debenzoyl-3'-(3-([¹²⁴I]-iodobenzoyl))paclitaxel analog as a radio-tracer to study multidrug resistance in vivo. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 70: 1624-31
Sun L, Veith JM, Pera P, et al. (2010) Design and synthesis of de novo cytotoxic alkaloids by mimicking the bioactive conformation of paclitaxel. Bioorganic & Medicinal Chemistry. 18: 7101-12
Shah DK, Shin BS, Veith J, et al. (2009) Use of an anti-vascular endothelial growth factor antibody in a pharmacokinetic strategy to increase the efficacy of intraperitoneal chemotherapy. The Journal of Pharmacology and Experimental Therapeutics. 329: 580-91
Kuznetsova LV, Pepe A, Ungureanu IM, et al. (2008) Syntheses and Structure-Activity Relationships of Novel 3'-Difluoromethyl and 3'-Trifluoromethyl-Taxoids. Journal of Fluorine Chemistry. 129: 817-828
Sun L, Geng X, Geney R, et al. (2008) Design, synthesis, and biological evaluation of novel C14-C3'BzN-linked macrocyclic taxoids. The Journal of Organic Chemistry. 73: 9584-93
Bernacki RJ. (2008) Metronomic chemotherapy and tumor immunomodulation. Cancer Biology & Therapy. 7: 602
Ojima I, Chen J, Sun L, et al. (2008) Design, synthesis, and biological evaluation of new-generation taxoids. Journal of Medicinal Chemistry. 51: 3203-21
Brooks TA, O'Loughlin KL, Minderman H, et al. (2007) The 4′-O-benzylated doxorubicin analog WP744 overcomes resistance mediated by P-glycoprotein, multidrug resistance protein and breast cancer resistance protein in cell lines and acute myeloid leukemia cells Investigational New Drugs. 25: 115-122
Bouvet M, Spernyak J, Katz MH, et al. (2005) High correlation of whole-body red fluorescent protein imaging and magnetic resonance imaging on an orthotopic model of pancreatic cancer. Cancer Research. 65: 9829-33
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