| Year |
Citation |
Score |
| 2012 |
Kuznetsova L, Sun L, Chen J, Zhao X, Seitz J, Das M, Li Y, Veith JM, Pera P, Bernacki RJ, Xia S, Horwitz SB, Ojima I. Synthesis and Biological Evaluation of Novel 3'-Difluorovinyl Taxoids. Journal of Fluorine Chemistry. 143: 177-188. PMID 23139432 DOI: 10.1016/J.Jfluchem.2012.07.007 |
0.418 |
|
| 2012 |
Sajjad M, Riaz U, Yao R, Bernacki RJ, Abouzied M, Erb DA, Chaudhary ND, Veith JM, Georg GI, Nabi HA. Investigation of 3'-debenzoyl-3'-(3-([¹²â´I]-iodobenzoyl))paclitaxel analog as a radio-tracer to study multidrug resistance in vivo. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 70: 1624-31. PMID 22738838 DOI: 10.1016/J.Apradiso.2012.03.008 |
0.732 |
|
| 2010 |
Sun L, Veith JM, Pera P, Bernacki RJ, Ojima I. Design and synthesis of de novo cytotoxic alkaloids by mimicking the bioactive conformation of paclitaxel. Bioorganic & Medicinal Chemistry. 18: 7101-12. PMID 20800500 DOI: 10.1016/J.Bmc.2010.07.069 |
0.369 |
|
| 2009 |
Shah DK, Shin BS, Veith J, Tóth K, Bernacki RJ, Balthasar JP. Use of an anti-vascular endothelial growth factor antibody in a pharmacokinetic strategy to increase the efficacy of intraperitoneal chemotherapy. The Journal of Pharmacology and Experimental Therapeutics. 329: 580-91. PMID 19233938 DOI: 10.1124/Jpet.108.149443 |
0.348 |
|
| 2008 |
Kuznetsova LV, Pepe A, Ungureanu IM, Pera P, Bernacki RJ, Ojima I. Syntheses and Structure-Activity Relationships of Novel 3'-Difluoromethyl and 3'-Trifluoromethyl-Taxoids. Journal of Fluorine Chemistry. 129: 817-828. PMID 19448839 DOI: 10.1016/J.Jfluchem.2008.05.013 |
0.364 |
|
| 2008 |
Sun L, Geng X, Geney R, Li Y, Simmerling C, Li Z, Lauher JW, Xia S, Horwitz SB, Veith JM, Pera P, Bernacki RJ, Ojima I. Design, synthesis, and biological evaluation of novel C14-C3'BzN-linked macrocyclic taxoids. The Journal of Organic Chemistry. 73: 9584-93. PMID 18975909 DOI: 10.1021/Jo801713Q |
0.324 |
|
| 2008 |
Bernacki RJ. Metronomic chemotherapy and tumor immunomodulation. Cancer Biology & Therapy. 7: 602. PMID 18614855 DOI: 10.4161/Cbt.7.4.5632 |
0.336 |
|
| 2008 |
Ojima I, Chen J, Sun L, Borella CP, Wang T, Miller ML, Lin S, Geng X, Kuznetsova L, Qu C, Gallager D, Zhao X, Zanardi I, Xia S, Horwitz SB, ... ... Bernacki RJ, et al. Design, synthesis, and biological evaluation of new-generation taxoids. Journal of Medicinal Chemistry. 51: 3203-21. PMID 18465846 DOI: 10.1021/Jm800086E |
0.489 |
|
| 2007 |
Brooks TA, O'Loughlin KL, Minderman H, Bundy BN, Ford LA, Vredenburg MR, Bernacki RJ, Priebe W, Baer MR. The 4′-O-benzylated doxorubicin analog WP744 overcomes resistance mediated by P-glycoprotein, multidrug resistance protein and breast cancer resistance protein in cell lines and acute myeloid leukemia cells Investigational New Drugs. 25: 115-122. PMID 17072745 DOI: 10.1007/S10637-006-9018-3 |
0.729 |
|
| 2005 |
Bouvet M, Spernyak J, Katz MH, Mazurchuk RV, Takimoto S, Bernacki R, Rustum YM, Moossa AR, Hoffman RM. High correlation of whole-body red fluorescent protein imaging and magnetic resonance imaging on an orthotopic model of pancreatic cancer. Cancer Research. 65: 9829-33. PMID 16267005 DOI: 10.1158/0008-5472.Can-05-1548 |
0.306 |
|
| 2005 |
Geney R, Sun L, Pera P, Bernacki RJ, Xia S, Horwitz SB, Simmerling CL, Ojima I. Use of the tubulin bound paclitaxel conformation for structure-based rational drug design. Chemistry & Biology. 12: 339-48. PMID 15797218 DOI: 10.1016/J.Chembiol.2005.01.004 |
0.396 |
|
| 2005 |
Ojima I, Borella CP, Wu X, Bounaud PY, Oderda CF, Sturm M, Miller ML, Chakravarty S, Chen J, Huang Q, Pera P, Brooks TA, Baer MR, Bernacki RJ. Design, synthesis and structure-activity relationships of novel taxane-based multidrug resistance reversal agents. Journal of Medicinal Chemistry. 48: 2218-28. PMID 15771464 DOI: 10.1021/Jm049483Y |
0.715 |
|
| 2004 |
Ramnath N, Hamm J, Schwartz G, Holden S, Eckhardt SG, Vredenburg MR, Bernacki RJ, Lathia C, Kanter P, Creaven PJ. A phase I and pharmacokinetic study of BAY59: a novel taxane. Oncology. 67: 123-9. PMID 15539916 DOI: 10.1159/000080998 |
0.712 |
|
| 2004 |
Brooks TA, Kennedy DR, Gruol DJ, Ojima I, Baer MR, Bernacki RJ. Structure-activity analysis of taxane-based broad-spectrum multidrug resistance modulators. Anticancer Research. 24: 409-15. PMID 15152938 |
0.698 |
|
| 2004 |
Minderman H, Brooks TA, O'Loughlin KL, Ojima I, Bernacki RJ, Baer MR. Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 59-8862) and tRA96023. Cancer Chemotherapy and Pharmacology. 53: 363-9. PMID 15060738 DOI: 10.1007/S00280-003-0745-2 |
0.708 |
|
| 2003 |
Brooks TA, Minderman H, O'Loughlin KL, Pera P, Ojima I, Baer MR, Bernacki RJ, Brooks T. Taxane-based reversal agents modulate drug resistance mediated by P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein. Molecular Cancer Therapeutics. 2: 1195-205. PMID 14617793 |
0.719 |
|
| 2003 |
Battaglia A, Bernacki RJ, Bertucci C, Bombardelli E, Cimitan S, Ferlini C, Fontana G, Guerrini A, Riva A. Synthesis and biological evaluation of 2'-methyl taxoids derived from baccatin III and 14beta-OH-baccatin III 1,14-carbonate. Journal of Medicinal Chemistry. 46: 4822-5. PMID 14584931 DOI: 10.1021/Jm034146V |
0.417 |
|
| 2003 |
Wu M, Mazurchuk R, Chaudhary ND, Spernyak J, Veith J, Pera P, Greco W, Hoffman RM, Kobayashi T, Bernacki RJ. High-resolution magnetic resonance imaging of the efficacy of the cytosine analogue 1-[2-C-cyano-2-deoxy-beta-D-arabino-pentofuranosyl]-N(4)-palmitoyl cytosine (CS-682) in a liver-metastasis athymic nude mouse model. Cancer Research. 63: 2477-82. PMID 12750269 |
0.685 |
|
| 2001 |
Chibale K, Ojima I, Haupt H, Geng X, Pera P, Bernacki RJ. Modulation of human mammary cell sensitivity to paclitaxel by new quinoline sulfonamides. Bioorganic & Medicinal Chemistry Letters. 11: 2457-60. PMID 11549446 DOI: 10.1016/S0960-894X(01)00462-0 |
0.451 |
|
| 2001 |
Vredenburg MR, Ojima I, Veith J, Pera P, Kee K, Cabral F, Sharma A, Kanter P, Greco WR, Bernacki RJ. Effects of orally active taxanes on P-glycoprotein modulation and colon and breast carcinoma drug resistance. Journal of the National Cancer Institute. 93: 1234-45. PMID 11504769 DOI: 10.1093/Jnci/93.16.1234 |
0.763 |
|
| 2001 |
Gruol DJ, Bernd J, Phippard AE, Ojima I, Bernacki RJ. The use of a novel taxane-based P-glycoprotein inhibitor to identify mutations that alter the interaction of the protein with paclitaxel Molecular Pharmacology. 60: 104-113. PMID 11408605 DOI: 10.1124/Mol.60.1.104 |
0.374 |
|
| 2000 |
Bernacki RJ, Pera P, Gambacorta P, Brun Y, Greco WR. In vitro antitumor activity of 9-nitro-camptothecin as a single agent and in combination with other antitumor drugs. Annals of the New York Academy of Sciences. 922: 293-7. PMID 11193904 DOI: 10.1111/J.1749-6632.2000.Tb07046.X |
0.436 |
|
| 2000 |
Ojima I, Lin S, Slater JC, Wang T, Pera P, Bernacki RJ, Ferlini C, Scambia G. Syntheses and biological activity of C-3'-difluoromethyl-taxoids. Bioorganic & Medicinal Chemistry. 8: 1619-28. PMID 10976509 DOI: 10.1016/S0968-0896(00)00093-6 |
0.426 |
|
| 1999 |
Dimitroff CJ, Pera P, Dall'Olio F, Matta KL, Chandrasekaran EV, Lau JT, Bernacki RJ. Cell surface n-acetylneuraminic acid alpha2,3-galactoside-dependent intercellular adhesion of human colon cancer cells. Biochemical and Biophysical Research Communications. 256: 631-6. PMID 10080950 DOI: 10.1006/Bbrc.1999.0388 |
0.331 |
|
| 1998 |
Ojima I, Bounaud PY, Takeuchi C, Pera P, Bernacki RJ. New taxanes as highly efficient reversal agents for multidrug resistance in cancer cells. Bioorganic & Medicinal Chemistry Letters. 8: 189-94. PMID 9871652 DOI: 10.1016/S0960-894X(97)10218-9 |
0.461 |
|
| 1998 |
Dimitroff CJ, Sharma A, Bernacki RJ. Cancer Metastasis: A Search for Therapeutic Inhibition Cancer Investigation. 16: 279-290. PMID 9589037 DOI: 10.3109/07357909809039778 |
0.33 |
|
| 1998 |
Ojima I, Lin S, Chakravarty S, Fenoglio I, Park YH, Sun C, Appendino G, Pera P, Veith JM, Bernacki RJ. Syntheses and Structure−Activity Relationships of Novel Nor-seco Taxoids The Journal of Organic Chemistry. 63: 1637-1645. DOI: 10.1021/Jo971953R |
0.31 |
|
| 1997 |
Sharma A, Mayhew E, Bolcsak L, Cavanaugh C, Harmon P, Janoff A, Bernacki RJ. Activity of paclitaxel liposome formulations against human ovarian tumor xenografts. International Journal of Cancer. Journal International Du Cancer. 71: 103-7. PMID 9096672 DOI: 10.1002/(Sici)1097-0215(19970328)71:1<103::Aid-Ijc17>3.0.Co;2-J |
0.358 |
|
| 1997 |
Ojima I, Slater JC, Kuduk SD, Takeuchi CS, Gimi RH, Sun CM, Park YH, Pera P, Veith JM, Bernacki RJ. Syntheses and structure-activity relationships of taxoids derived from 14 beta-hydroxy-10-deacetylbaccatin III. Journal of Medicinal Chemistry. 40: 267-78. PMID 9022793 DOI: 10.1021/Jm960563E |
0.412 |
|
| 1996 |
Ojima I, Slater JC, Michaud E, Kuduk SD, Bounaud PY, Vrignaud P, Bissery MC, Veith JM, Pera P, Bernacki RJ. Syntheses and structure-activity relationships of the second-generation antitumor taxoids: exceptional activity against drug-resistant cancer cells. Journal of Medicinal Chemistry. 39: 3889-96. PMID 8831755 DOI: 10.1021/Jm9604080 |
0.404 |
|
| 1995 |
Sharma A, Straubinger RM, Ojima I, Bernacki RJ. Antitumor efficacy of taxane liposomes on a human ovarian tumor xenograft in nude athymic mice Journal of Pharmaceutical Sciences. 84: 1400-1404. PMID 8748320 DOI: 10.1002/Jps.2600841204 |
0.353 |
|
| 1991 |
Sufrin JR, Spiess AJ, Kramer DL, Libby PR, Miller JT, Bernacki RJ, Lee YH, Borchardt RT, Porter CW. Targeting 5'-deoxy-5'-(methylthio)adenosine phosphorylase by 5'-haloalkyl analogues of 5'-deoxy-5'-(methylthio)adenosine. Journal of Medicinal Chemistry. 34: 2600-6. PMID 1908523 DOI: 10.1021/Jm00112A039 |
0.367 |
|
| 1990 |
Dutta SP, Bernacki RJ, Bloch A, Chheda GB. Synthesis and Biological Activity of 6-Hydroxyguanidino-and 6-Hydroxyureidopurine And Their Ribonucleosides Nucleosides, Nucleotides & Nucleic Acids. 9: 151-162. DOI: 10.1080/07328319008045127 |
0.308 |
|
| 1987 |
Niedbala MJ, Crickard K, Bernacki RJ. In vitro degradation of extracellular matrix by human ovarian carcinoma cells. Clinical & Experimental Metastasis. 5: 181-197. PMID 3297449 DOI: 10.1007/Bf00058063 |
0.353 |
|
| 1986 |
Bulbul MA, Pavelic K, Slocum HK, Frankfurt OS, Rustum YM, Huben RP, Bernacki RJ. Growth of human urologic tumors on extracellular matrix. The Journal of Urology. 136: 512-516. PMID 3735526 DOI: 10.1016/S0022-5347(17)44933-0 |
0.323 |
|
| 1985 |
Bernacki RJ, Niedbala MJ, Korytnyk W. Glycosidases in cancer and invasion. Cancer and Metastasis Reviews. 4: 81-101. PMID 3888385 DOI: 10.1007/Bf00047738 |
0.325 |
|
| 1985 |
Pavelic K, Beerman TA, Bernacki RJ. An evaluation of the effects of combination chemotherapy in vitro using DNA-reactive agents Cancer Drug Delivery. 2: 255-270. PMID 2415231 DOI: 10.1089/Cdd.1985.2.255 |
0.335 |
|
| 1984 |
Agostino MJ, Bernacki RJ, Beerman TA. Synergistic interactions of ethidium bromide and bleomycin on cellular DNA and growth inhibition Biochemical and Biophysical Research Communications. 120: 156-163. PMID 6201171 DOI: 10.1016/0006-291X(84)91427-X |
0.36 |
|
| 1983 |
Morin MJ, Porter CW, Petrie CR, Korytnyk W, Bernacki RJ. Effects of a membrane sugar analogue, 6-deoxy-6-fluoro-d-galactose, on the L1210 leukemic cell ectosialyltransferase system Biochemical Pharmacology. 32: 553-561. PMID 6847704 DOI: 10.1016/0006-2952(83)90538-5 |
0.31 |
|
| 1983 |
Morin MJ, Porter CW, McKernan P, Bernacki RJ. The biochemical and ultrastructural effects of tunicamycin and D-glucosamine in L1210 leukemic cells Journal of Cellular Physiology. 114: 162-172. PMID 6822608 DOI: 10.1002/Jcp.1041140204 |
0.327 |
|
| 1980 |
Paul B, Bernacki RJ, Korytnyk W. Synthesis and biological activity of some 1-N-substituted 2-acetamido-2-deoxy-β-d-glycopyranosylamine derivatives and related analogs Carbohydrate Research. 80: 99-115. PMID 7363276 DOI: 10.1016/S0008-6215(00)85318-5 |
0.325 |
|
| 1980 |
Sufrin JR, Bernacki RJ, Morin MJ, Korytnyk W. Halogenated L-fucose and D-galactose analogues: synthesis and metabolic effects. Journal of Medicinal Chemistry. 23: 143-9. PMID 7359528 DOI: 10.1021/Jm00176A008 |
0.316 |
|
| 1977 |
Bernacki RJ, Sharma M, Porter NK, Rustum Y, Paul B, Korytnyk W. Biochemical characteristics, metabolism, and antitumor activity of several acetylated hexosamines Journal of Supramolecular Structure. 7: 235-250. PMID 599936 DOI: 10.1002/Jss.400070208 |
0.337 |
|
| 1974 |
Bernacki RJ. Plasma membrane ectoglycosyltransferase activity of L1210 murine leukemic cells. Journal of Cellular Physiology. 83: 457-465. PMID 4363882 DOI: 10.1002/Jcp.1040830317 |
0.302 |
|
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