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Denis M. Grant

Affiliations: 
Pharmacology and Toxicology University of Toronto, Toronto, ON, Canada 
Area:
Pharmacology, Physiological Psychology
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Geoffrey H. Goodfellow grad student 2001 University of Toronto
Walter Swardfager grad student 2012 University of Toronto

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Wang S, Hanna D, Sugamori KS, et al. (2019) Primary aromatic amines and cancer: Novel mechanistic insights using 4-aminobiphenyl as a model carcinogen. Pharmacology & Therapeutics
Denis RGP, Busi F, Castel J, et al. (2019) A readout of metabolic efficiency in arylamine N-acetyltransferase-deficient mice reveals minor energy metabolism changes. Febs Letters
Gomez A, Bindesbøll C, Somisetty VS, et al. (2018) Characterization of TCDD-Inducible Poly-ADP-Ribose Polymerase (TIPARP/ARTD14) Catalytic Activity. The Biochemical Journal
Wang P, Shehu AI, Lu J, et al. (2017) Deficiency of N-Acetyltransferase Increases the Interactions of Isoniazid with Endobiotics in mouse Liver. Biochemical Pharmacology
Tseng CC, Noordali H, Sani M, et al. (2017) Development of Fluorinated Analogues of Perhexiline with Improved Pharmacokinetic Properties and Retained Efficacy. Journal of Medicinal Chemistry
Wang S, Bott D, Tung A, et al. (2015) Relative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult Mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 916-21
Wang S, Sugamori KS, Tung A, et al. (2015) N-hydroxylation of 4-aminobiphenyl by CYP2E1 produces oxidative stress in a mouse model of chemically induced liver cancer. Toxicological Sciences : An Official Journal of the Society of Toxicology. 144: 393-405
Witham KL, Butcher NJ, Sugamori KS, et al. (2013) 5-methyl-tetrahydrofolate and the S-adenosylmethionine cycle in C57BL/6J mouse tissues: gender differences and effects of arylamine N-acetyltransferase-1 deletion. Plos One. 8: e77923
Ogawa S, Surapisitchat J, Virtanen C, et al. (2013) Three-dimensional culture and cAMP signaling promote the maturation of human pluripotent stem cell-derived hepatocytes. Development (Cambridge, England). 140: 3285-96
Wang S, Sugamori KS, Grant DM. (2013) Abstract 4795: N-hydroxylation of 4-aminobiphenyl (ABP) and associated oxidative stress may influence ABP carcinogenicity in the mouse liver. Cancer Research. 73: 4795-4795
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