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Irwin Levitan, Ph.D.

Neuroscience Thomas Jefferson University 
Neuronal excitability
"Irwin Levitan"
Mean distance: 13.1 (cluster 11)
Cross-listing: Chemistry Tree

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Bukiya AN, Osborn CV, Kuntamallappanavar G, et al. (2015) Cholesterol increases the open probability of cardiac KACh currents. Biochimica Et Biophysica Acta
Rosenhouse-Dantsker A, Epshtein Y, Levitan I. (2014) Interplay Between Lipid Modulators of Kir2 Channels: Cholesterol and PIP2. Computational and Structural Biotechnology Journal. 11: 131-7
Han H, Rosenhouse-Dantsker A, Gnanasambandam R, et al. (2014) Silencing of Kir2 channels by caveolin-1: cross-talk with cholesterol. The Journal of Physiology. 592: 4025-38
Levitan I, Singh DK, Rosenhouse-Dantsker A. (2014) Cholesterol binding to ion channels. Frontiers in Physiology. 5: 65
Rosenhouse-Dantsker A, Noskov S, Durdagi S, et al. (2013) Identification of novel cholesterol-binding regions in Kir2 channels. The Journal of Biological Chemistry. 288: 31154-64
Rosenhouse-Dantsker A, Noskov S, Logothetis DE, et al. (2013) Cholesterol sensitivity of KIR2.1 depends on functional inter-links between the N and C termini. Channels (Austin, Tex.). 7: 303-12
Rosenhouse-Dantsker A, Noskov S, Han H, et al. (2012) Distant cytosolic residues mediate a two-way molecular switch that controls the modulation of inwardly rectifying potassium (Kir) channels by cholesterol and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)). The Journal of Biological Chemistry. 287: 40266-78
Deng W, Bukiya AN, Rodríguez-Menchaca AA, et al. (2012) Hypercholesterolemia induces up-regulation of KACh cardiac currents via a mechanism independent of phosphatidylinositol 4,5-bisphosphate and Gβγ. The Journal of Biological Chemistry. 287: 4925-35
Singh DK, Shentu TP, Enkvetchakul D, et al. (2011) Cholesterol regulates prokaryotic Kir channel by direct binding to channel protein. Biochimica Et Biophysica Acta. 1808: 2527-33
Ma H, Zhang J, Levitan IB. (2011) Slob, a Slowpoke channel-binding protein, modulates synaptic transmission. The Journal of General Physiology. 137: 225-38
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