David A. Hinkle, MD, PhD

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
astrocyte-mediated neuroprotection
Website:
http://www.pind.pitt.edu/old/PIND_Personnel/Hinkle.html
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Publications

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De Miranda BR, Rocha EM, Bai Q, et al. (2018) Astrocyte-specific DJ-1 overexpression protects against rotenone-induced neurotoxicity in a rat model of Parkinson's disease. Neurobiology of Disease. 115: 101-114
Mullett SJ, Di Maio R, Greenamyre JT, et al. (2013) DJ-1 expression modulates astrocyte-mediated protection against neuronal oxidative stress. Journal of Molecular Neuroscience : Mn. 49: 507-11
Larsen NJ, Ambrosi G, Mullett SJ, et al. (2011) DJ-1 knock-down impairs astrocyte mitochondrial function. Neuroscience. 196: 251-64
Mullett SJ, Hinkle DA. (2011) DJ-1 deficiency in astrocytes selectively enhances mitochondrial Complex I inhibitor-induced neurotoxicity. Journal of Neurochemistry. 117: 375-87
Mullett SJ, Hinkle DA. (2009) DJ-1 knock-down in astrocytes impairs astrocyte-mediated neuroprotection against rotenone. Neurobiology of Disease. 33: 28-36
Mullett SJ, Hamilton RL, Hinkle DA. (2009) DJ-1 immunoreactivity in human brain astrocytes is dependent on infarct presence and infarct age. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 29: 125-31
Bai Q, Mullett SJ, Garver JA, et al. (2006) Zebrafish DJ-1 is evolutionarily conserved and expressed in dopaminergic neurons. Brain Research. 1113: 33-44
Niu H, Hinkle DA, Wise PM. (1997) Dexamethasone regulates basic fibroblast growth factor, nerve growth factor and S100beta expression in cultured hippocampal astrocytes. Brain Research. Molecular Brain Research. 51: 97-105
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