Cynthia Czajkowski

Affiliations: 
University of Wisconsin, Madison, Madison, WI 
Area:
GABA(A) receptor structure-function
Website:
http://www.physiology.wisc.edu/faculty/czajkowski.html
Google:
"Cynthia Czajkowski"
Mean distance: 14.78 (cluster 11)
 
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Jeremy D. Bushman research assistant OHSU
Ross A. McDevitt research assistant 2001-2002 UW Madison
Kelly Christopherson grad student UW Madison
Jeremy Alden Teissere grad student 1997-2001 UW Madison
Jessica H. Holden grad student 2003 UW Madison
Lisa M. Sharkey grad student 2004 UW Madison
Feyza Sancar grad student 2006 UW Madison
Jose Mercado grad student 2007 UW Madison
Srinivasan P. Venkatachalan grad student 2004-2008 UW Madison
Michelle L. Perry grad student 2010 UW Madison
Cassandra M. Theusch grad student 2010 UW Madison
Kelly R. Wagoner grad student 2011 UW Madison
Elaine V. Morlock grad student 2012 UW Madison
Borna Ghosh grad student 2014 UW Madison
Susan Hanson post-doc UW Madison
David Wagner post-doc UW Madison
Andrew J Boileau research scientist UW Madison
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Publications

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Ghosh B, Tsao TW, Czajkowski C. (2017) A chimeric prokaryotic-eukaryotic pentameric ligand gated ion channel reveals interactions between the extracellular and transmembrane domains shape neurosteroid modulation. Neuropharmacology
Ding Y, Dellisanti CD, Ko MH, et al. (2014) The endoplasmic reticulum-based acetyltransferases, ATase1 and ATase2, associate with the oligosaccharyltransferase to acetylate correctly folded polypeptides. The Journal of Biological Chemistry. 289: 32044-55
Laha KT, Ghosh B, Czajkowski C. (2013) Macroscopic kinetics of pentameric ligand gated ion channels: comparisons between two prokaryotic channels and one eukaryotic channel. Plos One. 8: e80322
Dellisanti CD, Ghosh B, Hanson SM, et al. (2013) Site-directed spin labeling reveals pentameric ligand-gated ion channel gating motions. Plos Biology. 11: e1001714
Ghosh B, Satyshur KA, Czajkowski C. (2013) Propofol binding to the resting state of the gloeobacter violaceus ligand-gated ion channel (GLIC) induces structural changes in the inter- and intrasubunit transmembrane domain (TMD) cavities. The Journal of Biological Chemistry. 288: 17420-31
Venkatachalan SP, Czajkowski C. (2012) Structural link between γ-aminobutyric acid type A (GABAA) receptor agonist binding site and inner β-sheet governs channel activation and allosteric drug modulation. The Journal of Biological Chemistry. 287: 6714-24
Morlock EV, Czajkowski C. (2011) Different residues in the GABAA receptor benzodiazepine binding pocket mediate benzodiazepine efficacy and binding. Molecular Pharmacology. 80: 14-22
Dellisanti CD, Hanson SM, Chen L, et al. (2011) Packing of the extracellular domain hydrophobic core has evolved to facilitate pentameric ligand-gated ion channel function. The Journal of Biological Chemistry. 286: 3658-70
Sancar F, Czajkowski C. (2011) Allosteric modulators induce distinct movements at the GABA-binding site interface of the GABA-A receptor. Neuropharmacology. 60: 520-8
Hanson SM, Czajkowski C. (2011) Disulphide trapping of the GABA(A) receptor reveals the importance of the coupling interface in the action of benzodiazepines. British Journal of Pharmacology. 162: 673-87
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