Austen Milnerwood

Affiliations: 
2016- McGill University, Montreal, QC, Canada 
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"Austen Milnerwood"
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Parents

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Lynn Raymond grad student 2004-
Kerry PSJ Murphy grad student 2000-2004
Micheal G. Stewart grad student 2000-2004 The Open University

Children

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Stefano Cataldi grad student 2014-2018 UBC (FlyTree)
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Publications

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Bu M, Follett J, Deng I, et al. (2023) Inhibition of LRRK2 kinase activity rescues deficits in striatal dopamine physiology in VPS35 p.D620N knock-in mice. Npj Parkinson's Disease. 9: 167
Kadgien CA, Kamesh A, Milnerwood AJ. (2021) Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition. Molecular Brain. 14: 143
Kuhlmann N, Wagner Valladolid M, Quesada-Ramírez L, et al. (2021) Chronic and Acute Manipulation of Cortical Glutamate Transmission Induces Structural and Synaptic Changes in Co-cultured Striatal Neurons. Frontiers in Cellular Neuroscience. 15: 569031
Kuhlmann N, Milnerwood AJ. (2020) A Critical LRRK at the Synapse? The Neurobiological Function and Pathophysiological Dysfunction of LRRK2. Frontiers in Molecular Neuroscience. 13: 153
MacIsaac S, Quevedo Melo T, Zhang Y, et al. (2020) Neuron-autonomous susceptibility to induced synuclein aggregation is exacerbated by endogenous mutations and ameliorated by genetic knock-out. Brain Communications. 2: fcz052
Follett J, Fox JD, Gustavsson EK, et al. (2019) DNAJC13 p.Asn855Ser, implicated in familial parkinsonism, alters membrane dynamics of Sorting Nexin 1. Neuroscience Letters
Cataldi S, Follett J, Fox JD, et al. (2018) Altered dopamine release and monoamine transporters in Vps35 p.D620N knock-in mice. Npj Parkinson's Disease. 4: 27
Kovalenko M, Milnerwood A, Giordano J, et al. (2018) HttQ111/+ Huntington's Disease Knock-in Mice Exhibit Brain Region-Specific Morphological Changes and Synaptic Dysfunction. Journal of Huntington's Disease. 7: 17-33
Volta M, Beccano-Kelly DA, Paschall SA, et al. (2017) Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice. Elife. 6
Trinh J, Gustavsson EK, Vilariño-Güell C, et al. (2016) DNM3 and genetic modifiers of age of onset in LRRK2 Gly2019Ser parkinsonism: a genome-wide linkage and association study. The Lancet. Neurology
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