Austen Milnerwood - Publications

Affiliations: 
2016- McGill University, Montreal, QC, Canada 

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Follett J, Fox JD, Gustavsson EK, Kadgien C, Munsie LN, Cao LP, Tatarnikov I, Milnerwood AJ, Farrer MJ. DNAJC13 p.Asn855Ser, implicated in familial parkinsonism, alters membrane dynamics of Sorting Nexin 1. Neuroscience Letters. PMID 31082451 DOI: 10.1016/j.neulet.2019.04.043  0.56
2018 Cataldi S, Follett J, Fox JD, Tatarnikov I, Kadgien C, Gustavsson EK, Khinda J, Milnerwood AJ, Farrer MJ. Altered dopamine release and monoamine transporters in Vps35 p.D620N knock-in mice. Npj Parkinson's Disease. 4: 27. PMID 30155515 DOI: 10.1038/s41531-018-0063-3  0.56
2017 Volta M, Beccano-Kelly DA, Paschall SA, Cataldi S, MacIsaac SE, Kuhlmann N, Kadgien CA, Tatarnikov I, Fox J, Khinda J, Mitchell E, Bergeron S, Melrose H, Farrer MJ, Milnerwood AJ. Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice. Elife. 6. PMID 28930069 DOI: 10.7554/eLife.28377  0.56
2016 Trinh J, Gustavsson EK, Vilariño-Güell C, Bortnick S, Latourelle J, McKenzie MB, Tu CS, Nosova E, Khinda J, Milnerwood A, Lesage S, Brice A, Tazir M, Aasly JO, Parkkinen L, et al. DNM3 and genetic modifiers of age of onset in LRRK2 Gly2019Ser parkinsonism: a genome-wide linkage and association study. The Lancet. Neurology. PMID 27692902 DOI: 10.1016/S1474-4422(16)30203-4  0.56
2016 Volpicelli-Daley LA, Abdelmotilib H, Liu Z, Stoyka L, Daher JP, Milnerwood AJ, Unni VK, Hirst WD, Yue Z, Zhao HT, Fraser K, Kennedy RE, West AB. G2019S-LRRK2 Expression Augments α-Synuclein Sequestration into Inclusions in Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7415-27. PMID 27413152 DOI: 10.1523/JNEUROSCI.3642-15.2016  0.96
2016 Dallérac GM, Cummings DM, Hirst MC, Milnerwood AJ, Murphy KP. Changes in Dopamine Signalling Do Not Underlie Aberrant Hippocampal Plasticity in a Mouse Model of Huntington's Disease. Neuromolecular Medicine. PMID 26782175 DOI: 10.1007/s12017-016-8384-z  0.96
2015 Volta M, Milnerwood AJ, Farrer MJ. Insights from late-onset familial parkinsonism on the pathogenesis of idiopathic Parkinson's disease. The Lancet. Neurology. 14: 1054-64. PMID 26376970 DOI: 10.1016/S1474-4422(15)00186-6  0.96
2015 Volta M, Cataldi S, Beccano-Kelly D, Munsie L, Tatarnikov I, Chou P, Bergeron S, Mitchell E, Lim R, Khinda J, Lloret A, Bennett CF, Paradiso C, Morari M, Farrer MJ, ... Milnerwood AJ, et al. Chronic and acute LRRK2 silencing has no long-term behavioral effects, whereas wild-type and mutant LRRK2 overexpression induce motor and cognitive deficits and altered regulation of dopamine release. Parkinsonism & Related Disorders. 21: 1156-63. PMID 26282470 DOI: 10.1016/j.parkreldis.2015.07.025  0.96
2015 Dallérac GM, Levasseur G, Vatsavayai SC, Milnerwood AJ, Cummings DM, Kraev I, Huetz C, Evans KA, Walters SW, Rezaie P, Cho Y, Hirst MC, Murphy KP. Dysfunctional Dopaminergic Neurones in Mouse Models of Huntington's Disease: A Role for SK3 Channels. Neuro-Degenerative Diseases. 15: 93-108. PMID 25871323 DOI: 10.1159/000375126  0.96
2015 Beccano-Kelly DA, Volta M, Munsie LN, Paschall SA, Tatarnikov I, Co K, Chou P, Cao LP, Bergeron S, Mitchell E, Han H, Melrose HL, Tapia L, Raymond LA, Farrer MJ, ... Milnerwood AJ, et al. LRRK2 overexpression alters glutamatergic presynaptic plasticity, striatal dopamine tone, postsynaptic signal transduction, motor activity and memory. Human Molecular Genetics. 24: 1336-49. PMID 25343991 DOI: 10.1093/hmg/ddu543  0.96
2014 Beccano-Kelly DA, Kuhlmann N, Tatarnikov I, Volta M, Munsie LN, Chou P, Cao LP, Han H, Tapia L, Farrer MJ, Milnerwood AJ. Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice. Frontiers in Cellular Neuroscience. 8: 301. PMID 25309331 DOI: 10.3389/fncel.2014.00301  0.96
2014 Walker MD, Volta M, Cataldi S, Dinelle K, Beccano-Kelly D, Munsie L, Kornelsen R, Mah C, Chou P, Co K, Khinda J, Mroczek M, Bergeron S, Yu K, Cao LP, ... ... Milnerwood AJ, et al. Behavioral deficits and striatal DA signaling in LRRK2 p.G2019S transgenic rats: a multimodal investigation including PET neuroimaging. Journal of Parkinson's Disease. 4: 483-98. PMID 25000966 DOI: 10.3233/JPD-140344  0.96
2014 Araki E, Tsuboi Y, Daechsel J, Milnerwood A, Vilarino-Guell C, Fujii N, Mishima T, Oka T, Hara H, Fukae J, Farrer MJ. A novel DCTN1 mutation with late-onset parkinsonism and frontotemporal atrophy. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 1201-4. PMID 24676999 DOI: 10.1002/mds.25833  0.96
2014 Coquinco A, Kojic L, Wen W, Wang YT, Jeon NL, Milnerwood AJ, Cynader M. A microfluidic based in vitro model of synaptic competition. Molecular and Cellular Neurosciences. 60: 43-52. PMID 24662423 DOI: 10.1016/j.mcn.2014.03.001  0.96
2014 Brigidi GS, Sun Y, Beccano-Kelly D, Pitman K, Mobasser M, Borgland SL, Milnerwood AJ, Bamji SX. Palmitoylation of δ-catenin by DHHC5 mediates activity-induced synapse plasticity. Nature Neuroscience. 17: 522-32. PMID 24562000 DOI: 10.1038/nn.3657  0.96
2014 Vilariño-Güell C, Rajput A, Milnerwood AJ, Shah B, Szu-Tu C, Trinh J, Yu I, Encarnacion M, Munsie LN, Tapia L, Gustavsson EK, Chou P, Tatarnikov I, Evans DM, Pishotta FT, et al. DNAJC13 mutations in Parkinson disease. Human Molecular Genetics. 23: 1794-801. PMID 24218364 DOI: 10.1093/hmg/ddt570  0.96
2013 Milnerwood AJ, Parsons MP, Young FB, Singaraja RR, Franciosi S, Volta M, Bergeron S, Hayden MR, Raymond LA. Memory and synaptic deficits in Hip14/DHHC17 knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 110: 20296-301. PMID 24277827 DOI: 10.1073/pnas.1222384110  0.96
2012 Milnerwood AJ, Kaufman AM, Sepers MD, Gladding CM, Zhang L, Wang L, Fan J, Coquinco A, Qiao JY, Lee H, Wang YT, Cynader M, Raymond LA. Mitigation of augmented extrasynaptic NMDAR signaling and apoptosis in cortico-striatal co-cultures from Huntington's disease mice. Neurobiology of Disease. 48: 40-51. PMID 22668780 DOI: 10.1016/j.nbd.2012.05.013  0.96
2012 Gladding CM, Sepers MD, Xu J, Zhang LY, Milnerwood AJ, Lombroso PJ, Raymond LA. Calpain and STriatal-Enriched protein tyrosine phosphatase (STEP) activation contribute to extrasynaptic NMDA receptor localization in a Huntington's disease mouse model. Human Molecular Genetics. 21: 3739-52. PMID 22523092 DOI: 10.1093/hmg/dds154  0.96
2012 Kaufman AM, Milnerwood AJ, Sepers MD, Coquinco A, She K, Wang L, Lee H, Craig AM, Cynader M, Raymond LA. Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3992-4003. PMID 22442066 DOI: 10.1523/JNEUROSCI.4129-11.2012  0.96
2012 Fan J, Gladding CM, Wang L, Zhang LY, Kaufman AM, Milnerwood AJ, Raymond LA. P38 MAPK is involved in enhanced NMDA receptor-dependent excitotoxicity in YAC transgenic mouse model of Huntington disease. Neurobiology of Disease. 45: 999-1009. PMID 22198502 DOI: 10.1016/j.nbd.2011.12.019  0.96
2012 Petkau TL, Neal SJ, Milnerwood A, Mew A, Hill AM, Orban P, Gregg J, Lu G, Feldman HH, Mackenzie IR, Raymond LA, Leavitt BR. Synaptic dysfunction in progranulin-deficient mice. Neurobiology of Disease. 45: 711-22. PMID 22062772 DOI: 10.1016/j.nbd.2011.10.016  0.96
2011 Chartier-Harlin MC, Dachsel JC, Vilariño-Güell C, Lincoln SJ, Leprêtre F, Hulihan MM, Kachergus J, Milnerwood AJ, Tapia L, Song MS, Le Rhun E, Mutez E, Larvor L, Duflot A, Vanbesien-Mailliot C, et al. Translation initiator EIF4G1 mutations in familial Parkinson disease. American Journal of Human Genetics. 89: 398-406. PMID 21907011 DOI: 10.1016/j.ajhg.2011.08.009  0.96
2011 Tapia L, Milnerwood A, Guo A, Mills F, Yoshida E, Vasuta C, Mackenzie IR, Raymond L, Cynader M, Jia W, Bamji SX. Progranulin deficiency decreases gross neural connectivity but enhances transmission at individual synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11126-32. PMID 21813674 DOI: 10.1523/JNEUROSCI.6244-10.2011  0.96
2011 Singaraja RR, Huang K, Sanders SS, Milnerwood AJ, Hines R, Lerch JP, Franciosi S, Drisdel RC, Vaid K, Young FB, Doty C, Wan J, Bissada N, Henkelman RM, Green WN, et al. Altered palmitoylation and neuropathological deficits in mice lacking HIP14. Human Molecular Genetics. 20: 3899-909. PMID 21775500 DOI: 10.1093/hmg/ddr308  0.96
2010 Milnerwood AJ, Raymond LA. Early synaptic pathophysiology in neurodegeneration: insights from Huntington's disease. Trends in Neurosciences. 33: 513-23. PMID 20850189 DOI: 10.1016/j.tins.2010.08.002  0.96
2010 Milnerwood AJ, Gladding CM, Pouladi MA, Kaufman AM, Hines RM, Boyd JD, Ko RW, Vasuta OC, Graham RK, Hayden MR, Murphy TH, Raymond LA. Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice. Neuron. 65: 178-90. PMID 20152125 DOI: 10.1016/j.neuron.2010.01.008  0.96
2007 Milnerwood AJ, Raymond LA. Corticostriatal synaptic function in mouse models of Huntington's disease: early effects of huntingtin repeat length and protein load. The Journal of Physiology. 585: 817-31. PMID 17947312 DOI: 10.1113/jphysiol.2007.142448  0.96
2007 Cummings DM, Milnerwood AJ, Dallérac GM, Vatsavayai SC, Hirst MC, Murphy KP. Abnormal cortical synaptic plasticity in a mouse model of Huntington's disease. Brain Research Bulletin. 72: 103-7. PMID 17352933 DOI: 10.1016/j.brainresbull.2006.10.016  0.96
2007 Vatsavayai SC, Dallérac GM, Milnerwood AJ, Cummings DM, Rezaie P, Murphy KP, Hirst MC. Progressive CAG expansion in the brain of a novel R6/1-89Q mouse model of Huntington's disease with delayed phenotypic onset. Brain Research Bulletin. 72: 98-102. PMID 17352932 DOI: 10.1016/j.brainresbull.2006.10.015  0.72
2006 Cummings DM, Milnerwood AJ, Dallérac GM, Waights V, Brown JY, Vatsavayai SC, Hirst MC, Murphy KP. Aberrant cortical synaptic plasticity and dopaminergic dysfunction in a mouse model of Huntington's disease. Human Molecular Genetics. 15: 2856-68. PMID 16905556 DOI: 10.1093/hmg/ddl224  0.96
2006 Milnerwood AJ, Cummings DM, Dallérac GM, Brown JY, Vatsavayai SC, Hirst MC, Rezaie P, Murphy KP. Early development of aberrant synaptic plasticity in a mouse model of Huntington's disease. Human Molecular Genetics. 15: 1690-703. PMID 16600988 DOI: 10.1093/hmg/ddl092  0.96
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