Frank Heppner
Affiliations: | Neuropathology | Charité - Universitätsmedizin Berlin, Germany |
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Parents
Sign in to add mentor| Adriano Aguzzi | research scientist | University Hospital Zürich, Zürich, Switzerland |
Children
Sign in to add trainee| Stefan Prokop | post-doc | 2008-2015 | |
| Kelly R Miller | post-doc | 2009-2015 | Charité Berlin |
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Publications
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| Drost N, Houtman J, Cseresnyés Z, et al. (2020) The Amyloid-beta rich CNS environment alters myeloid cell functionality independent of their origin. Scientific Reports. 10: 7152 |
| Eede P, Obst J, Benke E, et al. (2020) Interleukin-12/23 deficiency differentially affects pathology in male and female Alzheimer's disease-like mice. Embo Reports. e48530 |
| Schwabenland M, Mossad O, Peres AG, et al. (2019) Loss of USP18 in microglia induces white matter pathology. Acta Neuropathologica Communications. 7: 106 |
| Houtman J, Freitag K, Gimber N, et al. (2019) Beclin1-driven autophagy modulates the inflammatory response of microglia via NLRP3. The Embo Journal |
| Kälin S, Miller KR, Kälin RE, et al. (2018) CNS myeloid cells critically regulate heat hyperalgesia. The Journal of Clinical Investigation |
| Capper D, Jones DTW, Sill M, et al. (2018) DNA methylation-based classification of central nervous system tumours. Nature |
| Radke J, Koll R, Preuße C, et al. (2018) Architectural B-cell organization in skeletal muscle identifies subtypes of dermatomyositis. Neurology(R) Neuroimmunology & Neuroinflammation. 5: e451 |
| Krasemann S, Madore C, Cialic R, et al. (2017) The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases. Immunity. 47: 566-581.e9 |
| Wagner LK, Gilling KE, Schormann E, et al. (2017) Immunoproteasome deficiency alters microglial cytokine response and improves cognitive deficits in Alzheimer's disease-like APPPS1 mice. Acta Neuropathologica Communications. 5: 52 |
| Baufeld C, Osterloh A, Prokop S, et al. (2016) High-fat diet-induced brain region-specific phenotypic spectrum of CNS resident microglia. Acta Neuropathologica |