Andrew Aguirre, M.D., Ph.D.
Affiliations: | Dana Farber Cancer Institute, Boston, MA, United States |
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| Tong X, Patel AS, Kim E, et al. (2024) Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer. Cancer Cell |
| Singh H, Sahgal P, Kapner K, et al. (2024) RAS/RAF co-mutation and ERBB2 copy number modulates HER2 heterogeneity and responsiveness to HER2-directed therapy in colorectal cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research |
| Schaefer A, Hodge RG, Zhang H, et al. (2023) RHOA drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling. Science Signaling. 16: eadg5289 |
| Singh H, Keller RB, Kapner KS, et al. (2023) Oncogenic drivers and therapeutic vulnerabilities in KRAS wild-type pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research |
| Qiang L, Hoffman MT, Ali LR, et al. (2023) TGFβ blockade in pancreatic cancer enhances sensitivity to combination chemotherapy. Gastroenterology |
| de Matos Simoes R, Shirasaki R, Downey-Kopyscinski SL, et al. (2023) Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias. Nature Cancer. 4: 754-773 |
| Koide E, Mohardt ML, Doctor ZM, et al. (2023) Development and characterization of selective FAK inhibitors and PROTACs with in vivo activity. Chembiochem : a European Journal of Chemical Biology. e202300141 |
| Perurena N, Lock R, Davis RA, et al. (2023) USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities. Cell Reports. Medicine. 101007 |
| Williams HL, Dias Costa A, Zhang J, et al. (2022) Spatially-resolved single-cell assessment of pancreatic cancer expression subtypes reveals co-expressor phenotypes and extensive intra-tumoral heterogeneity. Cancer Research |
| Ursu O, Neal JT, Shea E, et al. (2022) Author Correction: Massively parallel phenotyping of coding variants in cancer with Perturb-seq. Nature Biotechnology. 40: 1691 |