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Madhuja Samaddar

Affiliations: 
Indian Insitute of Science 
Area:
Biochemistry, Chaperones, Mitochondrial import
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"Madhuja Samaddar"
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Parents

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Patrick Raymond D’Silva grad student 2015 IISc Bangalore (Chemistry Tree)
Cynthia Kenyon post-doc UCSF

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Publications

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Samaddar M, Goudeau J, Sanchez M, et al. (2021) A genetic screen identifies new steps in oocyte maturation that enhance proteostasis in the immortal germ lineage. Elife. 10
Goudeau J, Samaddar M, Bohnert KA, et al. (2020) Addendum: A lysosomal switch triggers proteostasis renewal in the immortal C. elegans germ lineage. Nature. 580: E5
Bankapalli K, Saladi S, Awadia SS, et al. (2015) Robust Glyoxalase activity of Hsp31, a ThiJ/DJ-1/PfpI Family Member Protein, Is Critical for Oxidative Stress Resistance in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 290: 26491-507
Samaddar M, Goswami AV, Purushotham J, et al. (2014) Role of the loop L4,5 in allosteric regulation in mtHsp70s: in vivo significance of domain communication and its implications in protein translocation. Molecular Biology of the Cell. 25: 2129-42
Samaddar M, Goswami AV, Sinha D, et al. (2014) Understanding the Contribution of mtHsp70 towards Mitochondrial Dysfunction in Parkinson's Disease: A Yeast Model Biophysical Journal. 106: 186a
Goswami AV, Samaddar M, Sinha D, et al. (2012) Enhanced J-protein interaction and compromised protein stability of mtHsp70 variants lead to mitochondrial dysfunction in Parkinson's disease. Human Molecular Genetics. 21: 3317-32
Pareek G, Samaddar M, D'Silva P. (2011) Primary sequence that determines the functional overlap between mitochondrial heat shock protein 70 Ssc1 and Ssc3 of Saccharomyces cerevisiae. The Journal of Biological Chemistry. 286: 19001-13
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