Roman Sommer
Affiliations: | 2012-2016 | Helmholtz Institute for Pharmaceutical Research Saarland |
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"Roman Sommer"Parents
Sign in to add mentor| Ulrich Groth | grad student | 2011-2011 | University of Konstanz |
| Alexander Titz | grad student | 2012-2016 | Helmholtz Institute for Pharmaceutical Research Saarland |
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Publications
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| Siebert DCB, Sommer R, Pogorevc D, et al. (2019) Chemical synthesis of tripeptide thioesters for the biotechnological incorporation into the myxobacterial secondary metabolite argyrin via mutasynthesis. Beilstein Journal of Organic Chemistry. 15: 2922-2929 |
| Sommer R, Rox K, Wagner S, et al. (2019) Anti-Biofilm Agents against Pseudomonas aeruginosa: a Structure-Activity Relationship Study of C-Glycosidic LecB Inhibitors. Journal of Medicinal Chemistry |
| Taouai M, Chakroun K, Sommer R, et al. (2019) Glycocluster Tetrahydroxamic Acids Exhibiting Unprecedented Inhibition of Biofilms. Journal of Medicinal Chemistry |
| Lepsik M, Sommer R, Kuhaudomlarp S, et al. (2019) Induction of rare conformation of oligosaccharide by binding to calcium-dependent bacterial lectin: X-ray crystallography and modelling study. European Journal of Medicinal Chemistry. 177: 212-220 |
| Akduman N, Rödelsperger C, Sommer RJ. (2018) Culture-based analysis of Pristionchus-associated microbiota from beetles and figs for studying nematode-bacterial interactions. Plos One. 13: e0198018 |
| Sommer R, Makshakova ON, Wohlschlager T, et al. (2018) Crystal Structures of Fungal Tectonin in Complex with O-Methylated Glycans Suggest Key Role in Innate Immune Defense. Structure (London, England : 1993). 26: 391-402.e4 |
| Sommer R, Wagner S, Rox K, et al. (2017) Glycomimetic, orally bioavailable LecB inhibitors block biofilm formation of Pseudomonas aeruginosa. Journal of the American Chemical Society |
| Wagner S, Hauck D, Hoffmann M, et al. (2017) Covalent lectin inhibition and application in bacterial biofilm imaging. Angewandte Chemie (International Ed. in English) |
| Huggins WM, Minrovic BM, Corey BW, et al. (2017) 1,2,4-Triazolidine-3-thiones as Narrow Spectrum Antibiotics against Multidrug-Resistant Acinetobacter baumannii. Acs Medicinal Chemistry Letters. 8: 27-31 |
| Sommer R, Wagner S, Varrot A, et al. (2016) The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery. Chemical Science. 7: 4990-5001 |