Cheryl E.G. Leyns

Merck, Semoy, Centre-Val de Loire, France 
TREM2, tau, abeta, Alzheimer's disease, Parkinson's disease, LRRK2, GBA, synuclein
"Cheryl Leyns"
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Gratuze M, Leyns CE, Sauerbeck AD, et al. (2020) Impact of TREM2R47H variant on tau pathology-induced gliosis and neurodegeneration. The Journal of Clinical Investigation
Gallardo G, Wong CH, Ricardez SM, et al. (2019) Targeting tauopathy with engineered tau-degrading intrabodies. Molecular Neurodegeneration. 14: 38
Leyns CEG, Gratuze M, Narasimhan S, et al. (2019) TREM2 function impedes tau seeding in neuritic plaques. Nature Neuroscience
Gratuze M, Leyns CEG, Holtzman DM. (2018) New insights into the role of TREM2 in Alzheimer's disease. Molecular Neurodegeneration. 13: 66
Korlesky C, Kling PJ, Pham DQD, et al. (2018) Cord Blood Erythropoietin and Hepcidin Reflect Lower Newborn Iron Stores due to Maternal Obesity during Pregnancy. American Journal of Perinatology
Davis AA, Leyns CEG, Holtzman DM. (2018) Intercellular Spread of Protein Aggregates in Neurodegenerative Disease. Annual Review of Cell and Developmental Biology
Liao F1, Li A1, Xiong M1, et al. (2018) Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation. J Clin Invest.. 128: 2144-2155
Liao F, Li A, Xiong M, et al. (2018) Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation. The Journal of Clinical Investigation
Leyns CEG, Ulrich JD, Finn MB, et al. (2017) TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy. Proceedings of the National Academy of Sciences of the United States of America. 114: 11524-11529
Leyns CEG, Holtzman DM. (2017) Glial contributions to neurodegeneration in tauopathies. Molecular Neurodegeneration. 12: 50
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