Kelvin Luk
Affiliations: | McGill University, Montreal, QC, Canada |
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Centner A, Del Priore I, Chambers N, et al. (2024) Deficits in basal and evoked striatal dopamine release following alpha-synuclein preformed fibril injection: An in vivo microdialysis study. The European Journal of Neuroscience |
Patterson JR, Kochmanski J, Stoll AC, et al. (2024) Transcriptomic profiling of early synucleinopathy in rats induced with preformed fibrils. Npj Parkinson's Disease. 10: 7 |
Singh A, Panhelainen A, Reunanen S, et al. (2023) Combining fibril-induced alpha-synuclein aggregation and 6-hydroxydopamine in a mouse model of Parkinson's disease and the effect of cerebral dopamine neurotrophic factor on the induced neurodegeneration. The European Journal of Neuroscience. 59: 132-153 |
Boyd SL, Kuhn NC, Patterson JR, et al. (2023) Developmental exposure to the Parkinson's disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in α-synuclein pre-formed fibril (PFF)-injected mice. Toxicological Sciences : An Official Journal of the Society of Toxicology |
Steinkellner T, Conrad WS, Kovacs I, et al. (2021) Dopamine neurons exhibit emergent glutamatergic identity in Parkinson's disease. Brain : a Journal of Neurology |
Wu Q, Shaikh MA, Meymand ES, et al. (2020) Neuronal activity modulates alpha-synuclein aggregation and spreading in organotypic brain slice cultures and in vivo. Acta Neuropathologica |
Chmielarz P, Er Ş, Konovalova J, et al. (2020) GDNF/RET Signaling Pathway Activation Eliminates Lewy Body Pathology in Midbrain Dopamine Neurons. Movement Disorders : Official Journal of the Movement Disorder Society |
Hoban DB, Shrigley S, Mattsson B, et al. (2020) Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD. Proceedings of the National Academy of Sciences of the United States of America |
Wong YC, Luk K, Purtell K, et al. (2019) Neuronal vulnerability in Parkinson disease: Should the focus be on axons and synaptic terminals? Movement Disorders : Official Journal of the Movement Disorder Society |
Luk KC. (2019) Oxidative stress and α-synuclein conspire in vulnerable neurons to promote Parkinson's disease progression. The Journal of Clinical Investigation. 130 |