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Anastasia Khvorova

Affiliations: 
RNA Therapeutics Institute University Of Massachusetts Med Sch Worcester 
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Reka Agnes Haraszti grad student 2014-2018 University Of Massachusetts Med Sch Worcester
Daniel O'Reilly post-doc 2020- University of Massachusetts Medical School, USA (Chemistry Tree)
Bruno M.D.C. Godinho post-doc 2015-2019 University Of Massachusetts Med Sch Worcester

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Publications

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Gilbert JW, Kennedy Z, Godinho BMDC, et al. (2024) Identification of selective and non-selective targeting active siRNAs. Molecular Therapy. Nucleic Acids. 35: 102291
Rivera Flores IV, Monopoli K, Jackson S, et al. (2024) Near Sequence Homology Does Not Guarantee siRNA Cross-Species Efficacy. Nucleic Acid Therapeutics
Yamada K, Hariharan VN, Caiazzi J, et al. (2024) Enhancing siRNA efficacy in vivo with extended nucleic acid backbones. Nature Biotechnology
Allen S, O'Reilly D, Miller R, et al. (2024) mRNA Nuclear Clustering Leads to a Difference in Mutant Huntingtin mRNA and Protein Silencing by siRNAs . Nucleic Acid Therapeutics
Allen S, O'Reilly D, Miller R, et al. (2024) mRNA nuclear clustering leads to a difference in mutant huntingtin mRNA and protein silencing by siRNAs . Biorxiv : the Preprint Server For Biology
Belgrad J, Tang Q, Hildebrand S, et al. (2024) A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system. Nucleic Acids Research
Sarli SL, Fakih HH, Kelly K, et al. (2024) Quantifying the activity profile of ASO and siRNA conjugates in glioblastoma xenograft tumors in vivo. Nucleic Acids Research
Ferguson CM, Godinho BMDC, Echeverria D, et al. (2024) A combinatorial approach for achieving CNS-selective RNAi. Nucleic Acids Research
Belgrad J, Tang Q, Hildebrand S, et al. (2023) A programmable dual-targeting di-valent siRNA scaffold supports potent multi-gene modulation in the central nervous system. Biorxiv : the Preprint Server For Biology
Fakih HH, Tang Q, Summers A, et al. (2023) Dendritic amphiphilic siRNA: Selective albumin binding, efficacy, and low toxicity. Molecular Therapy. Nucleic Acids. 34: 102080
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