Alexander Silver

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2019- Cancer Biology Vanderbilt University, Nashville, TN 
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Haque T, Shastri A, Desai P, et al. (2024) A blueprint for pursuing therapeutic interventions and early phase clinical trials in clonal haematopoiesis. British Journal of Haematology
Mack T, Pershad Y, Vlasschaert C, et al. (2024) Germline genetics, disease, and exposure to medication influence longitudinal dynamics of clonal hematopoiesis. Haematologica
Meyer CT, Smith BN, Wang J, et al. (2024) Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies. Proceedings of the National Academy of Sciences of the United States of America. 121: e2408889121
Silver AJ, Brown DJ, Olmstead SD, et al. (2024) Repair of leukemia-associated single nucleotide variants via interallelic gene conversion. Biorxiv : the Preprint Server For Biology
Shannon ML, Heimlich JB, Olson S, et al. (2024) Clonal Hematopoiesis and Inflammation in the VasculaturE (CHIVE): a prospective, longitudinal cohort and biorepository. Blood Advances
Mack T, Vlasschaert C, von Beck K, et al. (2024) Cost-effective and scalable clonal hematopoiesis assay provides insight into clonal dynamics. The Journal of Molecular Diagnostics : Jmd
Silver AJ, Vlasschaert C, Mack T, et al. (2024) Solid organ transplant recipients exhibit more TET2-mutant clonal hematopoiesis of indeterminate potential not driven by increased transplantation risk. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Heimlich JB, Bhat P, Parker A, et al. (2024) Multiomic Profiling of Human Clonal Hematopoiesis Reveals Genotype and Cell-Specific Inflammatory Pathway Activation. Blood Advances
Monteith AJ, Ramsey HE, Silver AJ, et al. (2024) Lactate utilization enables metabolic escape to confer resistance to BET inhibition in acute myeloid leukemia. Cancer Research
Kishtagari A, Khan MAW, Li Y, et al. (2024) Driver mutation zygosity is a critical factor in predicting clonal hematopoiesis transformation risk. Blood Cancer Journal. 14: 6
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