Stephen Brown

2004-2009 Biology McMaster University, Hamilton, ON, Canada 
"Stephen Brown"
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Salman S, Brown ST, Nurse CA. (2012) Chronic nicotine induces hypoxia inducible factor-2α in perinatal rat adrenal chromaffin cells: role in transcriptional upregulation of KATP channel subunit Kir6.2. American Journal of Physiology. Cell Physiology. 302: C1531-8
Brown ST, Reyes EP, Nurse CA. (2011) Chronic hypoxia upregulates adenosine 2a receptor expression in chromaffin cells via hypoxia inducible factor-2α: role in modulating secretion. Biochemical and Biophysical Research Communications. 412: 466-72
Brown ST, Buttigieg J, Nurse CA. (2010) Divergent roles of reactive oxygen species in the responses of perinatal adrenal chromaffin cells to hypoxic challenges. Respiratory Physiology & Neurobiology. 174: 252-8
Nurse CA, Buttigieg J, Brown S, et al. (2009) Regulation of oxygen sensitivity in adrenal chromaffin cells. Annals of the New York Academy of Sciences. 1177: 132-9
Buttigieg J, Brown S, Holloway AC, et al. (2009) Chronic nicotine blunts hypoxic sensitivity in perinatal rat adrenal chromaffin cells via upregulation of KATP channels: role of alpha7 nicotinic acetylcholine receptor and hypoxia-inducible factor-2alpha. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7137-47
Brown ST, Kelly KF, Daniel JM, et al. (2009) Hypoxia inducible factor (HIF)-2 alpha is required for the development of the catecholaminergic phenotype of sympathoadrenal cells. Journal of Neurochemistry. 110: 622-30
Piskuric NA, Brown ST, Zhang M, et al. (2008) Glucosensing in an immortalized adrenomedullary chromaffin cell line: role of ATP-sensitive K+ channels. Neuroscience Letters. 445: 94-8
Brown ST, Nurse CA. (2008) Induction of HIF-2alpha is dependent on mitochondrial O2 consumption in an O2-sensitive adrenomedullary chromaffin cell line. American Journal of Physiology. Cell Physiology. 294: C1305-12
Buttigieg J, Brown ST, Lowe M, et al. (2008) Functional mitochondria are required for O2 but not CO2 sensing in immortalized adrenomedullary chromaffin cells. American Journal of Physiology. Cell Physiology. 294: C945-56
Buttigieg J, Brown S, Zhang M, et al. (2008) Chronic nicotine in utero selectively suppresses hypoxic sensitivity in neonatal rat adrenal chromaffin cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1317-26
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