Stephen G. Brohawn, PhD

Rockefeller University, New York, NY, United States 
 Molecular and Cell Biology University of California, Berkeley, Berkeley, CA 
Molecular basis of sensory transduction and cellular electrical signaling
"Stephen Brohawn"
Mean distance: 15.74 (cluster 11)
Cross-listing: Cell Biology Tree


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Thomas U. Schwartz grad student 2004-2010 MIT (Chemistry Tree)
Roderick MacKinnon post-doc 2010- Rockefeller
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Del Mármol J, Rietmeijer RA, Brohawn SG. (2018) Studying Mechanosensitivity of Two-Pore Domain K(+) Channels in Cellular and Reconstituted Proteoliposome Membranes. Methods in Molecular Biology (Clifton, N.J.). 1684: 129-150
Brohawn SG. (2015) How ion channels sense mechanical force: insights from mechanosensitive K2P channels TRAAK, TREK1, and TREK2. Annals of the New York Academy of Sciences. 1352: 20-32
Brohawn SG, Campbell EB, MacKinnon R. (2014) Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel. Nature. 516: 126-30
Brohawn SG, Su Z, MacKinnon R. (2014) Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K+ channels. Proceedings of the National Academy of Sciences of the United States of America. 111: 3614-9
Brohawn SG, Campbell EB, MacKinnon R. (2013) Domain-swapped chain connectivity and gated membrane access in a Fab-mediated crystal of the human TRAAK K+ channel. Proceedings of the National Academy of Sciences of the United States of America. 110: 2129-34
Brohawn SG, del Mármol J, MacKinnon R. (2012) Crystal structure of the human K2P TRAAK, a lipid- and mechano-sensitive K+ ion channel. Science (New York, N.Y.). 335: 436-41
Brohawn SG, Schwartz TU. (2009) Molecular architecture of the Nup84-Nup145C-Sec13 edge element in the nuclear pore complex lattice. Nature Structural & Molecular Biology. 16: 1173-7
Brohawn SG, Partridge JR, Whittle JR, et al. (2009) The nuclear pore complex has entered the atomic age. Structure (London, England : 1993). 17: 1156-68
Brohawn SG, Schwartz TU. (2009) A lattice model of the nuclear pore complex. Communicative & Integrative Biology. 2: 205-7
Leksa NC, Brohawn SG, Schwartz TU. (2009) The structure of the scaffold nucleoporin Nup120 reveals a new and unexpected domain architecture. Structure (London, England : 1993). 17: 1082-91
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